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A9KHD9

- G6PI_CLOPH

UniProt

A9KHD9 - G6PI_CLOPH

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Lachnoclostridium phytofermentans)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei290 – 2901Proton donorUniRule annotation
    Active sitei311 – 3111UniRule annotation
    Active sitei425 – 4251UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciCPHY357809:GHCL-462-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Cphy_0419
    OrganismiClostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Lachnoclostridium phytofermentans)
    Taxonomic identifieri357809 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
    ProteomesiUP000000370: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 449449Glucose-6-phosphate isomerasePRO_1000081235Add
    BLAST

    Proteomic databases

    PRIDEiA9KHD9.

    Interactioni

    Protein-protein interaction databases

    STRINGi357809.Cphy_0419.

    Structurei

    3D structure databases

    ProteinModelPortaliA9KHD9.
    SMRiA9KHD9. Positions 4-448.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiGVESYKR.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9KHD9-1 [UniParc]FASTAAdd to Basket

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    MAKVNFDYSI AKQFFSKEEL SYMKGAAEAA KQILLEKTGA GNDFLGWIDL    50
    PVDYDKEEFE RIITSAKKIQ SDSEVLLVIG IGGSYLGARA AIEFLRHSFY 100
    NSVSKEVRKT PEIYYVGNNI SSTYLSHLIE VIGDRDFSVN IISKSGTTTE 150
    PAIAFRIFKK LLIQKYGKVE AAKRIYATTD KSKGALKNLA TEEGYESFVV 200
    PDDVGGRFSV LTAVGLLPIA VSGADIKQLM DGAASMRERC LNNKFEENDS 250
    LLYASIRNIL LRKGKNIEIL ANYEPALHYV GEWWKQLYGE SEGKDKKGIF 300
    PASVDLTTDL HSMGQFIQDG QRTMFETVIN LEKSTCEVIL EEEDVDLDGL 350
    NYLAGKSVDF INKSAMKGTL LAHTDGDVPN LIVNIAEQSE FCLGELFYFF 400
    EFACGVSGYI LGVNPFDQPG VESYKKNMFA LLGKPGFEEL SKKLQERLQ 449
    Length:449
    Mass (Da):50,015
    Last modified:February 5, 2008 - v1
    Checksum:iC132535D783A3E3E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000885 Genomic DNA. Translation: ABX40806.1.
    RefSeqiWP_012198449.1. NC_010001.1.
    YP_001557545.1. NC_010001.1.

    Genome annotation databases

    EnsemblBacteriaiABX40806; ABX40806; Cphy_0419.
    GeneIDi5745179.
    KEGGicpy:Cphy_0419.
    PATRICi19500374. VBICloPhy16213_0429.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000885 Genomic DNA. Translation: ABX40806.1 .
    RefSeqi WP_012198449.1. NC_010001.1.
    YP_001557545.1. NC_010001.1.

    3D structure databases

    ProteinModelPortali A9KHD9.
    SMRi A9KHD9. Positions 4-448.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 357809.Cphy_0419.

    Proteomic databases

    PRIDEi A9KHD9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX40806 ; ABX40806 ; Cphy_0419 .
    GeneIDi 5745179.
    KEGGi cpy:Cphy_0419.
    PATRICi 19500374. VBICloPhy16213_0429.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi GVESYKR.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci CPHY357809:GHCL-462-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700394 / DSM 18823 / ISDg.

    Entry informationi

    Entry nameiG6PI_CLOPH
    AccessioniPrimary (citable) accession number: A9KHD9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3