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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Coxiella burnetii (strain Dugway 5J108-111)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:CBUD_2109
OrganismiCoxiella burnetii (strain Dugway 5J108-111)
Taxonomic identifieri434922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000008555 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001988901 – 592Arginine--tRNA ligaseAdd BLAST592

Proteomic databases

PRIDEiA9KH27

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA9KH27
SMRiA9KH27
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi134 – 144"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214
KOiK01887
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 2 hits
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A9KH27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDLSTMKQQ IETLLNQAIE RLKTKGVLKP EVTPVIKITH TTDPQHGDFA
60 70 80 90 100
TNLALTLSKA AGMRPHALAE KIVEALPPSG QITEVEIAGP GFINFFVTEG
110 120 130 140 150
SYQTVVSSIL KAGKDYGRSE MGKGQRVHME YVSANPTGPL HVGHGRGAAY
160 170 180 190 200
GACVANLLNA AGFEVHREYY VNDAGRQMGI LALSVWVRYL QGYEASIELP
210 220 230 240 250
KNAYQGEYII DIAEALKAKY GKQFYHSVES IQAKIPEEID SNADPEAYLD
260 270 280 290 300
AWVTAQKDLL GPKDFECVFQ AALDSILNDI KNDLEEFGVT YDDWFPESRL
310 320 330 340 350
VREGLIQEGL DLLTKHGYVY EKNGAQWFRA TALGDEKDRV LIRKNGLPTY
360 370 380 390 400
FAADVAYHLH KFNQGYDQII DIFGADHHGY IPRIRGFLKG LGKAPEKLHI
410 420 430 440 450
LLVQFAILYR GNEKVSMSTR GGTFVTLREL RHEVGNDAAR FFYIMRKPDQ
460 470 480 490 500
HLDFDLELAK SQSNENPVYY IQYAHARICS VFRQLKTTQK NWDRPRGMEN
510 520 530 540 550
LSLLSTNYEK ELLATLGRYP EVIKRAAMNY APHLLAHYLQ TLANQFHTYY
560 570 580 590
NAERFLIEDD NLRNARLNLI NAVQQIIRNG LTLLGVSAPE EM
Length:592
Mass (Da):66,806
Last modified:November 25, 2008 - v2
Checksum:i94B7C490266795D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000733 Genomic DNA Translation: ABS77583.2

Genome annotation databases

EnsemblBacteriaiABS77583; ABS77583; CBUD_2109
KEGGicbd:CBUD_2109

Similar proteinsi

Entry informationi

Entry nameiSYR_COXBN
AccessioniPrimary (citable) accession number: A9KH27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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