A9KH12 (ACYP_COXBN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	CBUD_2095

Organism

Coxiella burnetii (strain Dugway 5J108-111) [Complete proteome] [HAMAP]

Taxonomic identifier

434922 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	95 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.
Sequence caution	The sequence ABS77322.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 95	95	Acylphosphatase HAMAP MF_01450		PRO_0000326694
Regions
	Domain	10 – 95	86	Acylphosphatase-like
Sites
	Active site	25	1	By similarity
	Active site	43	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9KH12 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: FB7185A15315788F	FASTA	95	10,880
	10 20 30 40 50 60 MTQKEKNETC IHATVSGKVQ GVFFRESVRK KAEELQLTGW VKNLSHGDVE LVACGERDSI 70 80 90 MILTEWLWEG PPQAAVSNVN WEEIVVEDYS DFRVR

References

[1]

"Comparative genomics reveal extensive transposon-mediated genomic plasticity and diversity among potential effector proteins within the genus Coxiella." Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D., Williams K.P., Sobral B.W., Kupko J.J. III, Porcella S.F., Samuel J.E., Heinzen R.A. Infect. Immun. 77:642-656(2009) [PubMed: 19047403] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Dugway 5J108-111.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000733 Genomic DNA. Translation: ABS77322.2. Different initiation.
RefSeq	YP_001425399.2. NC_009727.1.
3D structure databases
ProteinModelPortal	A9KH12.
ModBase	Search...
Protein-protein interaction databases
STRING	A9KH12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5458709.
GenomeReviews	Gene locus CBUD_2095 in contig CP000733_GR.
KEGG	cbd:CBUD_2095.
PATRIC	17923981. VBICoxBur32972_2063.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG750266.
OMA	WCHTGSP.
ProtClustDB	PRK14437.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_COXBN

Accession

Primary (citable) accession number: A9KH12

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program