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Protein

UvrABC system protein C

Gene

uvrC

Organism
Coxiella burnetii (strain Dugway 5J108-111)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:CBUD_1276
OrganismiCoxiella burnetii (strain Dugway 5J108-111)
Taxonomic identifieri434922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000008555 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000777771 – 609UvrABC system protein CAdd BLAST609

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA9KFP2
SMRiA9KFP2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 92GIY-YIGUniRule annotationAdd BLAST78
Domaini202 – 237UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279961
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

A9KFP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIDNPSAFL KTLPTGSGVY QIQDAQGKVI YVGKARNLQK RVSSYFRRQL
60 70 80 90 100
DSKTQAMMAQ VQSIQTTITR NENEALLLEA SFIKQFRPRY NVLLRDDKSY
110 120 130 140 150
PYLYLATHQK FPRLDFYRGA KKAPGRYFGP YPNAGSVREN LALIQKLFKL
160 170 180 190 200
RQCSESFFKN RTRPCLQYQI KRCTAPCVGY VNEQEYRRQV EDAILFFEGK
210 220 230 240 250
NDQVIIKLTE RMEVASENLV FEEAAHYRDQ IRQLRRLQKQ QIITGGKGNI
260 270 280 290 300
DIIGIAESNG AIGFAILFIR SGRMIGHKPF FPNTPLGTTL QTALVEFIPQ
310 320 330 340 350
YYLSPLRNGD IPERIVTSEP LEDRLWIQRA LSSGLNRRLA ITDQKRAPYK
360 370 380 390 400
QWQAMAALNA AQALSQHLAQ KNTFALKLEA IQKSLALPNP IARIECFDIS
410 420 430 440 450
HTLGEATVAS CVVFGEEGLI KKDYRRFNIS GVTPGDDYGA LRQALTRRYV
460 470 480 490 500
RLKEGEGILP DVLLIDGGMG QLRQAAEVLE ELQVSGVILT AIAKGPGRKA
510 520 530 540 550
GLEKLFVWGR REEIHLPADN IAFHLIQQIR DEAHRFAITA HCNRRAKRRV
560 570 580 590 600
ESTLQEIEGI GPKRRQKLLK YFGGLQELQR ASIEEIARVP GVSETLAKAI

YDACHQHKG
Length:609
Mass (Da):69,061
Last modified:February 5, 2008 - v1
Checksum:i3617D3FFD3087FD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000733 Genomic DNA Translation: ABS77103.1
RefSeqiWP_011997009.1, NC_009727.1

Genome annotation databases

EnsemblBacteriaiABS77103; ABS77103; CBUD_1276
GeneIDi31483888
KEGGicbd:CBUD_1276

Similar proteinsi

Entry informationi

Entry nameiUVRC_COXBN
AccessioniPrimary (citable) accession number: A9KFP2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health