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Reviewed, UniProtKB/Swiss-Prot A9KC01 (HEM6_COXBN)

Last modified November 3, 2009. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: CBUD_0273
OrganismCoxiella burnetii (strain Dugway 5J108-111) [Complete proteome] [HAMAP]
Taxonomic identifier434922 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

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Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333
PRO_1000079255

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Sequences

Sequence LengthMass (Da)Tools
A9KC01-1 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 3859A8A6F02956C6

FASTA31036,496
        10         20         30         40         50         60 
MRKDRQNKIT EVGIYLKDLQ NRLCRAFEKE EGESRFQETL WEKPNGGGGR TRLLTEGHVI 

        70         80         90        100        110        120 
EQGGVNFSCV YGNQLPPAAT QKHPEISGFD FQAEGLSLVI HPRNPYVPTV HANFRFFIAG 

       130        140        150        160        170        180 
KDEADPRWWF GGGYDLTPYY GFEEDCRHWH RVAKKACDRF GEAIYPRFKA ACDDYFYLKH 

       190        200        210        220        230        240 
RNEPRGIGGL FFDDLNEWEF KRCFEFIKIL GDSFLEAYLP IMQNRKNHPY GERQREFQLY 

       250        260        270        280        290        300 
RRGRYVEFNL LYDRGTRFGL EFGGRTESIL MSLPPRVVWR PNWEPEPGSE EARLYEDYLV 

       310 
RRNWVSVSGA

« Hide

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References

[1]"Comparative genomics reveal extensive transposon-mediated genomic plasticity and diversity among potential effector proteins within the genus Coxiella."
Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D., Williams K.P., Sobral B.W., Kupko J.J. III, Porcella S.F., Samuel J.E., Heinzen R.A.
Infect. Immun. 77:642-656(2009) [PubMed: 19047403] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000733 Genomic DNA. Translation: ABS76568.2. Different initiation.
RefSeqYP_001423696.2.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5458570.
GenomeReviewsGene locus CBUD_0273 in contig CP000733_GR.
KEGGcbd:CBUD_0273.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVKAYLLD.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_COXBN
AccessionPrimary (citable) accession number: A9KC01
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents