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Protein
Submitted name:

Zgc:172162 protein

Gene

cblc

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zgc:172162 proteinImported
Gene namesi
Name:cblcImported
ORF Names:zgc:172162Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-080220-20. cblc.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiA9JRD3.

Expressioni

Gene expression databases

BgeeiENSDARG00000078217.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA9JRD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 330Cbl-PTB (Cbl-type phosphotyrosine-binding)InterPro annotationAdd BLAST308
Domaini360 – 399RING-typeInterPro annotationAdd BLAST40

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1785. Eukaryota.
ENOG410YDNH. LUCA.
HOGENOMiHOG000294176.
HOVERGENiHBG005255.
InParanoidiA9JRD3.
KOiK04707.
PhylomeDBiA9JRD3.
TreeFamiTF314210.

Family and domain databases

CDDicd00162. RING. 1 hit.
cd09920. SH2_Cbl-b_TKB. 1 hit.
Gene3Di1.20.930.20. 1 hit.
3.30.40.10. 1 hit.
3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR024162. Adaptor_Cbl.
IPR014741. Adaptor_Cbl_EF_hand-like.
IPR003153. Adaptor_Cbl_N_hlx.
IPR014742. Adaptor_Cbl_SH2-like.
IPR024159. Cbl_PTB.
IPR011992. EF-hand-dom_pair.
IPR000980. SH2.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
PANTHERiPTHR23007. PTHR23007. 1 hit.
PfamiView protein in Pfam
PF02262. Cbl_N. 1 hit.
PF02761. Cbl_N2. 1 hit.
PF02762. Cbl_N3. 1 hit.
SMARTiView protein in SMART
SM00184. RING. 1 hit.
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF47668. SSF47668. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiView protein in PROSITE
PS51506. CBL_PTB. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A9JRD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRPGTAGR SQISDTSETP SQPPTSADRK LLEKVLKRLD KLHKLSVDPR
60 70 80 90 100
LALKNSPPYL PELLSETAIH LTEVWAPYRG SAMAVPRWDE GDYMRIHIRH
110 120 130 140 150
LLDKTDRAVL LFKEGKEKMF EETSNYRRNL TKLSLLFSHM LNELRTIFPG
160 170 180 190 200
GRFQGDTYRV TKTEAKEFWR KTFGHKCIVQ WNVFKQQLKR VHYFEEGMEA
210 220 230 240 250
MALKSTVDLT CNDHISIFEF DIFTRLFQPW STLIRNWNHL AVTHPGYMAF
260 270 280 290 300
LTYDQVKARL EHYRHRPGSY IFRLSCTQMG QWAIGHVTSD GSIVQTIPQN
310 320 330 340 350
TPLYQALIQG FREGCYLYPD GRDVNPDLSS LCSPVHKGRV KVTEEQYELY
360 370 380 390 400
CEIGSTFQLC KICTERDKDT RIQPCGHLLC QPCLTGWQKS DGHTCPYCRC
410 420 430 440 450
DIRGTESILI EPYLPIRDKR AEEEEEDDED DDDDEEEDHE DIELVMKKLA
460 470 480 490
CMKKISQEEY QIPRSSLSPP PLPPKRNSSS PCPSPKPQTH RSFSLGAQK
Length:499
Mass (Da):57,763
Last modified:February 5, 2008 - v1
Checksum:iBA33A6D7BCC5FC7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC155616 mRNA. Translation: AAI55617.1.
RefSeqiNP_001121724.2. NM_001128252.1.
UniGeneiDr.118572.

Genome annotation databases

GeneIDi565383.
KEGGidre:565383.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA9JRD3_DANRE
AccessioniPrimary (citable) accession number: A9JRD3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 5, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)