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A9ITX6

- IF2_BORPD

UniProt

A9ITX6 - IF2_BORPD

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Protein

Translation initiation factor IF-2

Gene

infB

Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi501 – 5088GTPUniRule annotation
Nucleotide bindingi547 – 5515GTPUniRule annotation
Nucleotide bindingi601 – 6044GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBPET340100:GJBO-3172-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:Bpet3133
OrganismiBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Taxonomic identifieri340100 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
ProteomesiUP000001225: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 991991Translation initiation factor IF-2PRO_1000093760Add
BLAST

Proteomic databases

PRIDEiA9ITX6.

Interactioni

Protein-protein interaction databases

STRINGi340100.Bpet3133.

Structurei

3D structure databases

ProteinModelPortaliA9ITX6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini492 – 659168tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni501 – 5088G1By similarity
Regioni526 – 5305G2By similarity
Regioni547 – 5504G3By similarity
Regioni601 – 6044G4By similarity
Regioni637 – 6393G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
KOiK02519.
OMAiIIEVHVP.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9ITX6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSNTVAQFA TELKMPANVL LEQLRSAGVD LNSVDDAVTD SDKAKLLDSL
60 70 80 90 100
RRAHGATEGK KITLTRRQTS EIRQADATGR SRTIQVEVRK KRVFVKRDPS
110 120 130 140 150
EIALEQARAD AAASDAAPAE PAPAAAEPSA SAPVTAPVNA PAADAPQAPA
160 170 180 190 200
TAAPDTAAPA AETPSQPPAV EPQPAPVAQA EPEPQPEPVA KPAEAPAEPA
210 220 230 240 250
APAAVEAHAE REAEQAPPEP AVQAEIETAP APAAESAQAA RPEPVTPKAE
260 270 280 290 300
PAPAASKPAR AEGRRGAPVP VAAPAVDSAG REEARRAAEA EAAALREMLN
310 320 330 340 350
RPRKVLRAPE PEAGALSGTL HKPAGKAAAP GAKKDAKPGA GGSKKTIKTA
360 370 380 390 400
EVASTWSDDA SRKKPADTKS AAPSRDGWRA GGKGGKGGRN SRNQQAERRH
410 420 430 440 450
EPAPQEFIAR EVHVPETISV ADLAHKMSVK AAEVIKQLMK LGQMVTINQV
460 470 480 490 500
LDQETAMIVV EELGHVAIAA KLDDPEAFLD ETPVASEAEA LPRAPVVTVM
510 520 530 540 550
GHVDHGKTSL LDYIRRAKVA SGEAGGITQH IGAYHVETAR GVVTFLDTPG
560 570 580 590 600
HEAFTAMRAR GAKATDIVIL VVAADDGVMP QTREAIHHAK AGGVPLVVAV
610 620 630 640 650
NKIDKPEANP ERVKQELVAE EVVPEEYGGD VPFVPVSAKT GAGIDDLLEN
660 670 680 690 700
VLLQAEILEL TAPVEAPAKG LVIEARLDKG RGPVATILVQ SGTLKRGDVV
710 720 730 740 750
LAGASFGRVR AMVDENGKQI QEAGPSIPVE IQGLTEVPAA GDELIALADE
760 770 780 790 800
RKAREIALFR QGKFRDVKLA RQQAAKLESM FDNLGEGTQT LPLIVKTDVQ
810 820 830 840 850
GSQEALVASL TKLSTDEVRV QVVHAAVGGI SESDINLAIA SNAVVIGFNV
860 870 880 890 900
RAEQSAKKLA ESNGIDVRYY NIIYDAVDEV KAAMSGMLAP EKKEEVIGLV
910 920 930 940 950
EVREVYSISR IGNVAGCMVL DGLVRRDSQI RLLRNNVVHW TGHLDSLRRF
960 970 980 990
KDDVKEVKSG FDCGLTLRGS NDIQVGDQLE VFEIKEIART L
Length:991
Mass (Da):104,344
Last modified:February 5, 2008 - v1
Checksum:i90A833E9BB4D7211
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM902716 Genomic DNA. Translation: CAP43475.1.
RefSeqiWP_012250037.1. NC_010170.1.
YP_001631743.1. NC_010170.1.

Genome annotation databases

EnsemblBacteriaiCAP43475; CAP43475; Bpet3133.
GeneIDi5816972.
KEGGibpt:Bpet3133.
PATRICi21167819. VBIBorPet31633_3158.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM902716 Genomic DNA. Translation: CAP43475.1 .
RefSeqi WP_012250037.1. NC_010170.1.
YP_001631743.1. NC_010170.1.

3D structure databases

ProteinModelPortali A9ITX6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 340100.Bpet3133.

Proteomic databases

PRIDEi A9ITX6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP43475 ; CAP43475 ; Bpet3133 .
GeneIDi 5816972.
KEGGi bpt:Bpet3133.
PATRICi 21167819. VBIBorPet31633_3158.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
KOi K02519.
OMAi IIEVHVP.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci BPET340100:GJBO-3172-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-461 / DSM 12804 / CCUG 43448.

Entry informationi

Entry nameiIF2_BORPD
AccessioniPrimary (citable) accession number: A9ITX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3