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A9ITX6 (IF2_BORPD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-2
Gene names
Name:infB
Ordered Locus Names:Bpet3133
OrganismBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]
Taxonomic identifier340100 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length991 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity. HAMAP-Rule MF_00100

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00100.

Sequence similarities

Belongs to the IF-2 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

GTPase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

translation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 991991Translation initiation factor IF-2 HAMAP-Rule MF_00100
PRO_1000093760

Regions

Nucleotide binding501 – 5088GTP By similarity
Nucleotide binding547 – 5515GTP By similarity
Nucleotide binding601 – 6044GTP By similarity
Region495 – 643149G-domain HAMAP-Rule MF_00100

Sequences

Sequence LengthMass (Da)Tools
A9ITX6 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 90A833E9BB4D7211

FASTA991104,344
        10         20         30         40         50         60 
MSSNTVAQFA TELKMPANVL LEQLRSAGVD LNSVDDAVTD SDKAKLLDSL RRAHGATEGK 

        70         80         90        100        110        120 
KITLTRRQTS EIRQADATGR SRTIQVEVRK KRVFVKRDPS EIALEQARAD AAASDAAPAE 

       130        140        150        160        170        180 
PAPAAAEPSA SAPVTAPVNA PAADAPQAPA TAAPDTAAPA AETPSQPPAV EPQPAPVAQA 

       190        200        210        220        230        240 
EPEPQPEPVA KPAEAPAEPA APAAVEAHAE REAEQAPPEP AVQAEIETAP APAAESAQAA 

       250        260        270        280        290        300 
RPEPVTPKAE PAPAASKPAR AEGRRGAPVP VAAPAVDSAG REEARRAAEA EAAALREMLN 

       310        320        330        340        350        360 
RPRKVLRAPE PEAGALSGTL HKPAGKAAAP GAKKDAKPGA GGSKKTIKTA EVASTWSDDA 

       370        380        390        400        410        420 
SRKKPADTKS AAPSRDGWRA GGKGGKGGRN SRNQQAERRH EPAPQEFIAR EVHVPETISV 

       430        440        450        460        470        480 
ADLAHKMSVK AAEVIKQLMK LGQMVTINQV LDQETAMIVV EELGHVAIAA KLDDPEAFLD 

       490        500        510        520        530        540 
ETPVASEAEA LPRAPVVTVM GHVDHGKTSL LDYIRRAKVA SGEAGGITQH IGAYHVETAR 

       550        560        570        580        590        600 
GVVTFLDTPG HEAFTAMRAR GAKATDIVIL VVAADDGVMP QTREAIHHAK AGGVPLVVAV 

       610        620        630        640        650        660 
NKIDKPEANP ERVKQELVAE EVVPEEYGGD VPFVPVSAKT GAGIDDLLEN VLLQAEILEL 

       670        680        690        700        710        720 
TAPVEAPAKG LVIEARLDKG RGPVATILVQ SGTLKRGDVV LAGASFGRVR AMVDENGKQI 

       730        740        750        760        770        780 
QEAGPSIPVE IQGLTEVPAA GDELIALADE RKAREIALFR QGKFRDVKLA RQQAAKLESM 

       790        800        810        820        830        840 
FDNLGEGTQT LPLIVKTDVQ GSQEALVASL TKLSTDEVRV QVVHAAVGGI SESDINLAIA 

       850        860        870        880        890        900 
SNAVVIGFNV RAEQSAKKLA ESNGIDVRYY NIIYDAVDEV KAAMSGMLAP EKKEEVIGLV 

       910        920        930        940        950        960 
EVREVYSISR IGNVAGCMVL DGLVRRDSQI RLLRNNVVHW TGHLDSLRRF KDDVKEVKSG 

       970        980        990 
FDCGLTLRGS NDIQVGDQLE VFEIKEIART L 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM902716 Genomic DNA. Translation: CAP43475.1.
RefSeqYP_001631743.1. NC_010170.1.

3D structure databases

ProteinModelPortalA9ITX6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340100.Bpet3133.

Proteomic databases

PRIDEA9ITX6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP43475; CAP43475; Bpet3133.
GeneID5816972.
KEGGbpt:Bpet3133.
PATRIC21167819. VBIBorPet31633_3158.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0532.
HOGENOMHOG000076907.
KOK02519.
OMAIIEVHVP.
OrthoDBEOG67HJSV.

Enzyme and pathway databases

BioCycBPET340100:GJBO-3172-MONOMER.

Family and domain databases

Gene3D3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_00100_B. IF_2_B.
InterProIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS01176. IF2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF2_BORPD
AccessionPrimary (citable) accession number: A9ITX6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries