Reviewed, UniProtKB/Swiss-Prot A9IT47 (AROC_BORPD)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	Bpet3039

Organism

Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]

Taxonomic identifier

340100 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 352	352	Chorismate synthase HAMAP MF_00300		PRO_1000115330

Sequences

	Sequence		Length	Mass (Da)
	A9IT47-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 3E4399656D6003A6	FASTA	352	37,220
	10 20 30 40 50 60 MSGNTLGTLF CVTNFGESHG PAIGCVVDGC PPGLALDAAD IQAELDRRRP GTSRHVTQRQ 70 80 90 100 110 120 EADQVEILSG VYQGVTTGTP IALLIRNTDA RSKDYSNIAD TFRPGHADFT YTRKYGLRDP 130 140 150 160 170 180 RGGGRSSARL TAPTVAAGAI AKKWLAEHHG VRVRGYMSQL GPIAIPFVSW DDVPANPFYA 190 200 210 220 230 240 PNAAIVPELE AYMDQLRRDG DSVGARIEVV AENLPAGWGE PLYDRLDADI AHVMMGLNAV 250 260 270 280 290 300 KGVSIGAGFG CIAQRGSEHG DEITPDGFVG NNAGGVLGGI STGQPVTVSL AIKPTSSIRV 310 320 330 340 350 ERRSVNSAGE PVMVQTLGRH DPCVGIRATP IAEAMLALVL IDHALRHRAQ CG

References

[1]

"The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae." Gross R., Guzman C.A., Sebaihia M., Martin dos Santos V.A.P., Pieper D.H., Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V., Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S., Linke B., Meyer F. , Mormann S., Nakunst D., Rueckert C., Schneiker-Bekel S., Schulze K., Voerholter F.-J., Yevsa T., Engle J.T., Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O., Martinez-Arias R. BMC Genomics 9:449-449(2008) [PubMed: 18826580] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM902716 Genomic DNA. Translation: CAP43381.1.
RefSeq	YP_001631649.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5817463.
GenomeReviews	Gene locus Bpet3039 in contig AM902716_GR.
KEGG	bpt:Bpet3039.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SRFTTQR.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BORPD

Accession

Primary (citable) accession number: A9IT47

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 5, 2008
Last modified:	November 3, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)