A9ISY2 (A9ISY2_BORPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrolipoamide acetyltranferase EMBL CAP43360.1
EC=2.3.1.12 EMBL CAP43360.1

Gene names

Name:	aceF EMBL CAP43360.1
Ordered Locus Names:	Bpet3018

Organism

Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]

Taxonomic identifier

340100 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella › Bordetella petrii

Protein attributes

Sequence length	563 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423 Contains 2 lipoyl-binding domains. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl SAAS SAAS003016 RuleBase RU000447
Molecular function	Acyltransferase RuleBase RU003765 EMBL CAP43360.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: InterPro
Cellular_component	pyruvate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	dihydrolipoyllysine-residue acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9ISY2 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 51178C889F4ACF4D	FASTA	563	58,393
	10 20 30 40 50 60 MSKLVEIKVP DIGDFKEVEV IEVLVSEGDT IQAEQSLITV ESDKASMEIP ASSGGVVKSV 70 80 90 100 110 120 KVKVGDKVAE GKVILEVEAG EAAGADQAPA SPDKADAAAK QPSSGDAPKT QGQTVEAPDV 130 140 150 160 170 180 KPAADAGKGA GGIAEITVPD IGDFKEVEVI EVMIAVGDTI KPEQSLITVE SDKASMEIPA 190 200 210 220 230 240 SAGGVVKEVK VKVGDKVAKG TAIAVVEGQG GAQAEPQKAQ APAQAQEQQP SGAASASAAA 250 260 270 280 290 300 PAPAAKPAPA AALEDPGLKP GQLPHASPSV RKFARELGVN LSKVKGSGPK DRITADDVRA 310 320 330 340 350 360 FVKQALAAPA AAAGGADGAA LGLLPWPKVD FTKFGPVEAK PLSRIKKISG ANLHRNWVMI 370 380 390 400 410 420 PHVTNNDEAD ITDLEALRVT LNKENEKAGI KVTMLAFLIK AVVAALKKFP EFNASLDGDQ 430 440 450 460 470 480 LVYKQYYHIG FAADTPNGLV VPVIRDADKK GILEIAKEMG ELSKKARDGK ISPAEMQGGC 490 500 510 520 530 540 FSISSLGGIG GTHFTPIINA PEVAILGVSR SAHKPVWDGK QFVPRLIVPL SLSYDHRVID 550 560 GAAAARFNAY LGQLLADFRR IVL

References

[1]

"The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae." Gross R., Guzman C.A., Sebaihia M., Martins Dos Santos V.A., Pieper D.H., Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V., Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S., Linke B., Meyer F. , Mormann S., Nakunst D., Rueckert C., Schneiker-Bekel S., Schulze K., Vorhoelter F.J., Yevsa T., Engle J.T., Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O., Martinez-Arias R. BMC Genomics 9:449-449(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-461 / DSM 12804 / CCUG 43448.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM902716 Genomic DNA. Translation: CAP43360.1.
RefSeq	YP_001631628.1. NC_010170.1.
3D structure databases
ProteinModelPortal	A9ISY2.
SMR	A9ISY2. Positions 6-83, 133-212, 324-563.
ModBase	Search...
Protein-protein interaction databases
STRING	340100.Bpet3018.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAP43360; CAP43360; Bpet3018.
GeneID	5817454.
KEGG	bpt:Bpet3018.
PATRIC	21167575. VBIBorPet31633_3041.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0508.
HOGENOM	HOG000281562.
KO	K00627.
OMA	VPMTRLM.
ProtClustDB	PRK11855.
Enzyme and pathway databases
BioCyc	BPET340100:GJBO-3053-MONOMER.
Family and domain databases
Gene3D	3.30.559.10. 1 hit. 4.10.320.10. 1 hit.
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR006256. AcTrfase_Pyrv_DH_cplx. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 2 hits. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 2 hits.
TIGRFAMs	TIGR01348. PDHac_trf_long. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 2 hits. PS00189. LIPOYL. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9ISY2_BORPD

Accession

Primary (citable) accession number: A9ISY2

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)