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A9IQN4 (AROC_BART1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:BT_0645
OrganismBartonella tribocorum (strain CIP 105476 / IBS 506) [Complete proteome] [HAMAP]
Taxonomic identifier382640 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Chorismate synthase HAMAP MF_00300
PRO_1000078985

Sequences

Sequence LengthMass (Da)Tools
A9IQN4 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 466B55D7B3A44C7B

FASTA36239,159
        10         20         30         40         50         60 
MSHNTFGHLF RVTTWGESHG AALGCVIDGC PPGIIFTLAE IQAYLDKRRP GQSKYTTQRQ 

        70         80         90        100        110        120 
EQDQVELLSG AITQEDGTTF VTTGTPISLL IRNTDQRSQD YGKIAHQYRP GHADYTYDVK 

       130        140        150        160        170        180 
YGIRDFRGGG RASARETAAR VAAGALARKV VPHLVVRGAV IAIGPHHINR DRWDWSEVEN 

       190        200        210        220        230        240 
NPFFTADAEM VQIFSDYIRK IRKDGTSVGA VIEIVAENVP AGLGAPIYAK LDQDIASLLM 

       250        260        270        280        290        300 
SINAVKGVEI GDGFAAARLR GEENADEMRM GNDGKPLFLS NHAGGILGGI SSGQPIIARF 

       310        320        330        340        350        360 
AVKPTSSILT PRRSIDVDGH DVDVITKGRH DPCVGIRAVP VGEAMVACAL ADHYLRHRGQ 


VG

« Hide

References

[1]"Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors."
Saenz H.L., Engel P., Stoeckli M.C., Lanz C., Raddatz G., Vayssier-Taussat M., Birtles R., Schuster S.C., Dehio C.
Nat. Genet. 39:1469-1476(2007) [PubMed: 18037886] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CIP 105476 / IBS 506.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM260525 Genomic DNA. Translation: CAK01080.1.
RefSeqYP_001609075.1. NC_010161.1.

3D structure databases

ProteinModelPortalA9IQN4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9IQN4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5830322.
GenomeReviewsGene locus BT_0645 in contig AM260525_GR.
PATRIC20549048. VBIBarTri113218_0683.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycBTRI382640:BT_0645-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_BART1
AccessionPrimary (citable) accession number: A9IQN4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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