A9IPK0 (A9IPK0_BORPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE1 EMBL CAP42955.1
Synonyms:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Bpet2613

Organism

Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]

Taxonomic identifier

340100 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	1065 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9IPK0 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 39C537FA7A80A758	FASTA	1,065	116,729
	10 20 30 40 50 60 MSSAMPSAIS STPSSALLPA YAELQCLSNF SFLQGASRPE ELVAQAAQLG YAALAITDEC 70 80 90 100 110 120 SLAGVVRAHV AAKSCELPLI IGSTLALQGS ADAPGPTLVL LAQNREGYGN LSELITLGRS 130 140 150 160 170 180 RAPKGQYRLC ADDIAAPGPG HAHLRGVPDC LAILAPPDSI DADTLARQAA WLARTFPGRA 190 200 210 220 230 240 WVGLTLLHRA RDDLHRAAVQ QAAQAAALPM VALGRVQMHL RSRKPLHDTL AAIRSKRSVA 250 260 270 280 290 300 QCGYDLQANA EQHLRTRLRL ASLYPADALA QTLVIAQRCS FSLDTLRYEY PDEIVPAGET 310 320 330 340 350 360 PASYLRREVY AGARGRYHGD VPASVTAQIE KELTLITELK YEPYFLTVYD IVQEARRRNI 370 380 390 400 410 420 LCQGRGSAAN SVVCYCLGIT AVAPEQSKAL FERFISKERR EPPDIDVDFE HQRREEIIQY 430 440 450 460 470 480 IYDKYGRHRA ALTGVVITYR PRSVLRDTGR ALGVDLGIID AVARAHQWWD GRQAMLRTLG 490 500 510 520 530 540 NCGLDPDSRV ARHWAVLAET LIGFPRHLSQ HPGGFVISRG NLARLVPIEN AAMPDRSVVQ 550 560 570 580 590 600 WDKDDLDALG LLKVDILALG MLSVLHRALD LTAQRRGQPL ALHEIPQDDE ATYDMICDAD 610 620 630 640 650 660 TVGVFQIESR AQMSMLPRLR PREYYDLVVQ VAIVRPGPIQ GGMVHPYLKR RQGLEDETYP 670 680 690 700 710 720 SEAVRGVLSR TKGVPIFQEQ VMQIAMVAAG FSAGEADELR RSMAAWKRKG GIDKYTDKLV 730 740 750 760 770 780 AGLLKNNYSA EFAAAIIRQI EGFGEYGFPE SHAASFALLA YASSWLKRHE PEAFLAALLN 790 800 810 820 830 840 SQPMGFYAPA QLVQDARRHG VVVLPADAAV SCWEAALENL PAPPGQPPAR PAVRLGLNQV 850 860 870 880 890 900 QGLSEDAGRR IEQARAARPY TDTRDLGRRA ALSRHELDAL AAADALRSLA GHRRLASWEA 910 920 930 940 950 960 SASVAHRDLL RDADVAEAAT PVLPAPTEGQ SISADYRSLR LTLRRHPVAL LRPRLRALRF 970 980 990 1000 1010 1020 ETAAVLRHYP DRRLARACGL VTVRQRPQTA KGTIFVTLED ETGPVNVVVR NELIERQRRE 1030 1040 1050 1060 LLGATLLGVY GTWQSASGVH HLIAQRLVDL SALLGGLPAR SRNFH

References

[1]

"The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae." Gross R., Guzman C.A., Sebaihia M., Martin dos Santos V.A.P., Pieper D.H., Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V., Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S., Linke B., Meyer F. , Mormann S., Nakunst D., Rueckert C., Schneiker-Bekel S., Schulze K., Voerholter F.-J., Yevsa T., Engle J.T., Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O., Martinez-Arias R. BMC Genomics 9:449-449(2008) [PubMed: 18826580] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM902716 Genomic DNA. Translation: CAP42955.1.
RefSeq	YP_001631223.1. NC_010170.1.
3D structure databases
ProteinModelPortal	A9IPK0.
ModBase	Search...
Protein-protein interaction databases
STRING	A9IPK0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5819940.
GenomeReviews	Gene locus Bpet2613 in contig AM902716_GR.
KEGG	bpt:Bpet2613.
PATRIC	21166712. VBIBorPet31633_2618.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	EQPAIRL.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9IPK0_BORPD

Accession

Primary (citable) accession number: A9IPK0

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)