A9IP97 (DADA_BORPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	Bpet2578

Organism

Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]

Taxonomic identifier

340100 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	434 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 434	434	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000138639
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	A9IP97 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 2FFD8FF3F281B5DB	FASTA	434	46,814
	10 20 30 40 50 60 MHVIVLGSGV IGTTTAYYLA RQGAKVTVLD RQPEAACETS YANAGQVSPG YSTPWAAPGI 70 80 90 100 110 120 PFKALKWLFQ KDAPLAIRPD GTLYQWRWMA AMLANCTAGR YTVNKERMLR LAEYSRDCLR 130 140 150 160 170 180 ELRADTGIQY EARTLGTLQL FRSASQYQAA QRDIQVLDAC GVPYELLDSA RLQTVEPALA 190 200 210 220 230 240 RTAHKLAGGL RLPNDETGDC RLFTRRLAQL AAGLGVEFRY GQDVEALVAG GAEIRGVRVG 250 260 270 280 290 300 GETLAADRYV AAFGSYTRGF LAPLGLELPV YPVKGYSLTI PLASAEAAPV STVLDETYKV 310 320 330 340 350 360 AITRFDNRIR VGGMAELAGF DLGLNPAHRR TLEHVVTDLY PGCGEVAQAE FWTGLRPMTP 370 380 390 400 410 420 DSTPIVGATR YANLFLNTGH GTLGWTMACG SGKVVADLVT GQRPAIRADD LALARYQAAQ 430 TRHAGPALGE RSAA

References

[1]

"The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae." Gross R., Guzman C.A., Sebaihia M., Martin dos Santos V.A.P., Pieper D.H., Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V., Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S., Linke B., Meyer F. , Mormann S., Nakunst D., Rueckert C., Schneiker-Bekel S., Schulze K., Voerholter F.-J., Yevsa T., Engle J.T., Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O., Martinez-Arias R. BMC Genomics 9:449-449(2008) [PubMed: 18826580] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-461 / DSM 12804 / CCUG 43448.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM902716 Genomic DNA. Translation: CAP42920.1.
RefSeq	YP_001631188.1. NC_010170.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A9IP97.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5816765.
GenomeReviews	Gene locus Bpet2578 in contig AM902716_GR.
KEGG	bpt:Bpet2578.
PATRIC	21166638. VBIBorPet31633_2581.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG729204.
OMA	NCTAAHY.
ProtClustDB	PRK00711.
Enzyme and pathway databases
BioCyc	BPET94624:BPET2578-MONOMER.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_BORPD

Accession

Primary (citable) accession number: A9IP97

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program