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A9IM91 (PSD_BORPD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Bpet2337
OrganismBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]
Taxonomic identifier340100 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 253253Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131350
Chain254 – 28835Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131351

Sites

Site253 – 2542Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2541Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A9IM91 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 36AA5884F26BEF0B

FASTA28831,800
        10         20         30         40         50         60 
MLFKDQLFLA SQYAAPHHLV SRLMGLAADC RTPAIKNWMI SRFVRRYGVD MSEALVQDPL 

        70         80         90        100        110        120 
AYDTFNQFFT RKLRADARPL DTEPGAVLCP ADGAISQLGP IEHGRIFQAK GHSYSLTSLL 

       130        140        150        160        170        180 
GGDPARAEPF MGGDFATIYL SPRDYHRVHM PCAGTLREMV HVPGRLFSVN PLTATHVPEL 

       190        200        210        220        230        240 
FARNERVACL FDTEYGPMAM VLVGAMIVAS IETAWAGLVT PHKRQIRAQR YDEAARAPIH 

       250        260        270        280 
LDKGAEMGLF KLGSTVIVLF GPGRVRWTDT PSVRGPVRMG ELLALPKA

« Hide

References

[1]"The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae."
Gross R., Guzman C.A., Sebaihia M., Martin dos Santos V.A.P., Pieper D.H., Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V., Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S., Linke B., Meyer F. expand/collapse author list , Mormann S., Nakunst D., Rueckert C., Schneiker-Bekel S., Schulze K., Voerholter F.-J., Yevsa T., Engle J.T., Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O., Martinez-Arias R.
BMC Genomics 9:449-449(2008) [PubMed: 18826580] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-461 / DSM 12804 / CCUG 43448.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM902716 Genomic DNA. Translation: CAP42680.1.
RefSeqYP_001630948.1. NC_010170.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA9IM91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5817660.
GenomeReviewsGene locus Bpet2337 in contig AM902716_GR.
KEGGbpt:Bpet2337.
PATRIC21166138. VBIBorPet31633_2331.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG302256.
OMASMATVWH.
ProtClustDBPRK00044.

Enzyme and pathway databases

BioCycBPET94624:BPET2337-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BORPD
AccessionPrimary (citable) accession number: A9IM91
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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