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A9ILN1 (PNCB_BART1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BT_0089
OrganismBartonella tribocorum (strain CIP 105476 / IBS 506) [Complete proteome] [HAMAP]
Taxonomic identifier382640 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146831

Sequences

Sequence LengthMass (Da)Tools
A9ILN1 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: F00387A91F670DBE

FASTA43450,207
        10         20         30         40         50         60 
MNHPDIARRV YNHTWKLDPI IRSLLDTDFY KLLMVQMIWG LYPTVNVTFS LINRTKTIRL 

        70         80         90        100        110        120 
ADDIDESELR AQLDHALSLR FTKKEMIWLA GNTFYGRKQI FEPDFLQWLE NFQLPEYELA 

       130        140        150        160        170        180 
RKDGQYILHF HGSWAHSSMW EIPALAIISE LRSRAALKKL DRFALDVLYA RAKAKMWRKV 

       190        200        210        220        230        240 
ERLKKLPDIK ISDFGTRRRH SFLWQRWCVE ALKEGIGDSF TGTSNVLLAM DTDLEALGTN 

       250        260        270        280        290        300 
AHELPMVIAA LSNNDDELRR APYQVLQDWN RYYGGNLLIV LPDTFGTEAF LCDAPDWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIEGGERIIQ WWKEKGQDPR EKLLIFSDAL DVDTIEKTYH HFHGKVRMSF 

       370        380        390        400        410        420 
GWGTDLTNDF TGCAPQEIAT LDALSLVCKV THANGRPAVK LSDNPEKTIG DSKEVQRYLN 

       430 
FFGNKKRVAR PVKM 

« Hide

References

[1]"Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors."
Saenz H.L., Engel P., Stoeckli M.C., Lanz C., Raddatz G., Vayssier-Taussat M., Birtles R., Schuster S.C., Dehio C.
Nat. Genet. 39:1469-1476(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CIP 105476 / IBS 506.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM260525 Genomic DNA. Translation: CAK00583.1.
RefSeqYP_001608578.1. NC_010161.1.

3D structure databases

ProteinModelPortalA9ILN1.
SMRA9ILN1. Positions 1-425.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING382640.Btr_0089.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5830201.
KEGGbtr:Btr_0089.
PATRIC20547894. VBIBarTri113218_0111.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000274489.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycBTRI382640:GJEK-79-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BART1
AccessionPrimary (citable) accession number: A9ILN1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways