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A9ILJ3

- DAPD_BART1

UniProt

A9ILJ3 - DAPD_BART1

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Protein

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Gene

dapD

Organism
Bartonella tribocorum (strain CIP 105476 / IBS 506)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei109 – 1091SubstrateUniRule annotation
Binding sitei146 – 1461SubstrateUniRule annotation

GO - Molecular functioni

  1. 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. diaminopimelate biosynthetic process Source: UniProtKB-HAMAP
  2. lysine biosynthetic process via diaminopimelate Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Diaminopimelate biosynthesis, Lysine biosynthesis

Enzyme and pathway databases

BioCyciBTRI382640:GJEK-66-MONOMER.
UniPathwayiUPA00034; UER00019.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferaseUniRule annotation (EC:2.3.1.117UniRule annotation)
Alternative name(s):
Tetrahydrodipicolinate N-succinyltransferaseUniRule annotation
Short name:
THDP succinyltransferaseUniRule annotation
Short name:
THP succinyltransferaseUniRule annotation
Short name:
Tetrahydropicolinate succinylaseUniRule annotation
Gene namesi
Name:dapDUniRule annotation
Ordered Locus Names:BT_0075
OrganismiBartonella tribocorum (strain CIP 105476 / IBS 506)
Taxonomic identifieri382640 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000001592: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2862862,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferasePRO_1000083745Add
BLAST

Interactioni

Subunit structurei

Homotrimer.UniRule annotation

Protein-protein interaction databases

STRINGi382640.Btr_0075.

Structurei

3D structure databases

ProteinModelPortaliA9ILJ3.
SMRiA9ILJ3. Positions 4-281.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transferase hexapeptide repeat family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG2171.
HOGENOMiHOG000027983.
KOiK00674.
OMAiYIARNTV.
OrthoDBiEOG68H8BV.

Family and domain databases

Gene3Di1.10.166.10. 1 hit.
HAMAPiMF_00811. DapD.
InterProiIPR005664. DapD_Trfase_Hexpep_rpt_fam.
IPR001451. Hexapep_transf.
IPR023180. THP_succinylTrfase_dom1.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PANTHERiPTHR19136:SF52. PTHR19136:SF52. 1 hit.
PfamiPF00132. Hexapep. 1 hit.
PF14805. THDPS_N_2. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
TIGRFAMsiTIGR00965. dapD. 1 hit.

Sequencei

Sequence statusi: Complete.

A9ILJ3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTHLTQLEII IEKAFDDRDS INTTTKGEIR ESVEHTLSLL DKGEIRVAER
60 70 80 90 100
QKNGQWYVHQ WLKKAVLLSF RLNPMQIITG GINGTHWWDK VPSKFSGWKE
110 120 130 140 150
DDFQKAGFRS VPGAIVRHSA YVAPNVILMP SFINLGAFVD EGTMVDTWTT
160 170 180 190 200
VGSCAQIGKH VHLSGGVGIG GVLEPLQANP TIIEDHCFIG ARSEVVEGCI
210 220 230 240 250
IREGAVLGMG VFIGQSTKII DRTTGEIFIG EVPAYSVVVP GSLPGKPLPN
260 270 280
GEAGPNLYCA VIVKRVDQKT REKTSINELL RDETQC
Length:286
Mass (Da):31,376
Last modified:February 5, 2008 - v1
Checksum:iC6A3360F20E28420
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260525 Genomic DNA. Translation: CAK00571.1.
RefSeqiWP_012230384.1. NC_010161.1.
YP_001608566.1. NC_010161.1.

Genome annotation databases

GeneIDi5829884.
KEGGibtr:Btr_0075.
PATRICi20547866. VBIBarTri113218_0098.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260525 Genomic DNA. Translation: CAK00571.1 .
RefSeqi WP_012230384.1. NC_010161.1.
YP_001608566.1. NC_010161.1.

3D structure databases

ProteinModelPortali A9ILJ3.
SMRi A9ILJ3. Positions 4-281.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 382640.Btr_0075.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5829884.
KEGGi btr:Btr_0075.
PATRICi 20547866. VBIBarTri113218_0098.

Phylogenomic databases

eggNOGi COG2171.
HOGENOMi HOG000027983.
KOi K00674.
OMAi YIARNTV.
OrthoDBi EOG68H8BV.

Enzyme and pathway databases

UniPathwayi UPA00034 ; UER00019 .
BioCyci BTRI382640:GJEK-66-MONOMER.

Family and domain databases

Gene3Di 1.10.166.10. 1 hit.
HAMAPi MF_00811. DapD.
InterProi IPR005664. DapD_Trfase_Hexpep_rpt_fam.
IPR001451. Hexapep_transf.
IPR023180. THP_succinylTrfase_dom1.
IPR011004. Trimer_LpxA-like.
[Graphical view ]
PANTHERi PTHR19136:SF52. PTHR19136:SF52. 1 hit.
Pfami PF00132. Hexapep. 1 hit.
PF14805. THDPS_N_2. 1 hit.
[Graphical view ]
SUPFAMi SSF51161. SSF51161. 1 hit.
TIGRFAMsi TIGR00965. dapD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors."
    Saenz H.L., Engel P., Stoeckli M.C., Lanz C., Raddatz G., Vayssier-Taussat M., Birtles R., Schuster S.C., Dehio C.
    Nat. Genet. 39:1469-1476(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CIP 105476 / IBS 506.

Entry informationi

Entry nameiDAPD_BART1
AccessioniPrimary (citable) accession number: A9ILJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3