A9ILB0 (A9ILB0_BART1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898

Gene names

Name:	gyrB HAMAP MF_01898 EMBL CAK00544.1
Ordered Locus Names:	BT_0041

Organism

Bartonella tribocorum (strain CIP 105476 / IBS 506) [Complete proteome] [HAMAP]

Taxonomic identifier

382640 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	816 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380 Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9ILB0 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: EB5A68DB0019B2CF	FASTA	816	90,289
	10 20 30 40 50 60 MSDEITSPTQ STSPTKGDDY GAASIKVLKG LDAVRKRPGM YIGDTDDGSG LHHMVYEVVD 70 80 90 100 110 120 NAIDEALAGH ATLVNVTLHA DGSCSVRDNG RGIPTDIHPT EGISAAEVIM TQLHAGGKFD 130 140 150 160 170 180 QNSYKVSGGL HGVGVSVVNA LSVWLKLQIR RNGKIHEISF THGVADAPLK VVGDCDQESG 190 200 210 220 230 240 TEIRFLPSSE TFTMVEFDFE TLERRLRELA FLNSGVHILL VDERHADIKA VELHYEGGLI 250 260 270 280 290 300 EFVKYIDQSK KALLDTPIYI ASEKDGMSVD VALWWNDSYH EKVLCFTNNI PQRDGGTHLI 310 320 330 340 350 360 GFRSALTRQI NGYAESSGIA KKEKVNLTGD DCREGLTAIL SVKVPDPKFS SQTKDKLVSS 370 380 390 400 410 420 EVRPIVENLV NEGLSTWLEE HPNEAKLLIS KVVEAATARE AARKARELTR RKGALDITSL 430 440 450 460 470 480 PGKLADCQER DPAKSEIFIV EGDSAGGSAK SGRSRQNQAI LPLRGKILNV ERARFDRMLS 490 500 510 520 530 540 SDMIGTLITA LGTSIGKDEF SPDKLRYHKI IIMTDADVDG AHIRTLLLTF FFRQMPELIE 550 560 570 580 590 600 RGHLYIAQPP LYKVSRGKSS QYIKNEAAFE EFLIDTGLEE TTLELSTGEV RAGADLYQLA 610 620 630 640 650 660 KDARVFRQLL NGLHTRYDRN VVEQAAIVGA FNPEAFATQE KAQKIAEAVE HRLNLIADDM 670 680 690 700 710 720 EQGWSGQYIE DGSLCFERIL RGVKDVITLD AGLINSADAR QIDRISQNFS DLYHPPLLLR 730 740 750 760 770 780 RKDKTERIFG PMSLLESIFT NGKKGITLQR YKGLGEMNAE QLWETTLDPN ARSLLQVKIN 790 800 810 DATDADSLFS RLMGDEVEPR RIFIQDNALS VANLDI

References

[1]

"Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors." Saenz H.L., Engel P., Stoeckli M.C., Lanz C., Raddatz G., Vayssier-Taussat M., Birtles R., Schuster S.C., Dehio C. Nat. Genet. 39:1469-1476(2007) [PubMed: 18037886] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM260525 Genomic DNA. Translation: CAK00544.1.
RefSeq	YP_001608539.1. NC_010161.1.
3D structure databases
ProteinModelPortal	A9ILB0.
SMR	A9ILB0. Positions 25-394.
ModBase	Search...
Protein-protein interaction databases
STRING	A9ILB0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5828872.
GenomeReviews	Gene locus BT_0041 in contig AM260525_GR.
PATRIC	20547796. VBIBarTri113218_0063.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	PRK14939.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9ILB0_BART1

Accession

Primary (citable) accession number: A9ILB0

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)