Reviewed, UniProtKB/Swiss-Prot A9IJI7 (AROA_BORPD)

Names and origin

Protein names

Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferase
    EC=2.5.1.19
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthase
      Short name=EPSP synthase
      Short name=EPSPS

Gene names

Name:	aroA
Ordered Locus Names:	Bpet1888

Organism

Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]

Taxonomic identifier

340100 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the EPSP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210		PRO_1000099667

Sequences

	Sequence		Length	Mass (Da)
	A9IJI7-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 05FA30C6FD96E8C4	FASTA	447	47,356
	10 20 30 40 50 60 MTGQPYLDLP RARQARGQVA LPGSKSISNR VLLLAALAAG RTDISGLLDS DDTRVMLAAL 70 80 90 100 110 120 RQLGVELAEA GEGRVTVGGA GRFPVKQADL FLGNAGTAFR PLTAALALMG GQYRLSGVPR 130 140 150 160 170 180 MHERPIGDLV DALRQWGARI DYLGQAGYPP LAVGEGRIRA DAPARVQGAV SSQFLTALLL 190 200 210 220 230 240 AAPVLAQGSD RPVVIEVAGE LISKPYIEIT LNLMARYGVQ VRRDGWRTFT IEPGAAYRSP 250 260 270 280 290 300 GAIAVEGDAS SASYFLALGA IGGGPVRVTG VGADSIQGDV AFARTLADMG VQIDYGPDWI 310 320 330 340 350 360 EARGVRVDQG GRLKAFDTDF NLIPDAAMTA AALALYADGP CRLRNIGSWR VKETDRIHAM 370 380 390 400 410 420 HTELAKLGAE VESGPDWLRI TPPADGGWRD AHIGTWDDHR MAMCFSLAAF GPAAVRILDP 430 440 GCVSKTFPDY FDVYAGLVSG APDSYDD

References

[1]

"The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae." Gross R., Guzman C.A., Sebaihia M., Martin dos Santos V.A.P., Pieper D.H., Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V., Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S., Linke B., Meyer F. , Mormann S., Nakunst D., Rueckert C., Schneiker-Bekel S., Schulze K., Voerholter F.-J., Yevsa T., Engle J.T., Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O., Martinez-Arias R. BMC Genomics 9:449-449(2008) [PubMed: 18826580] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM902716 Genomic DNA. Translation: CAP42227.1.
RefSeq	YP_001630496.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5819144.
GenomeReviews	Gene locus Bpet1888 in contig AM902716_GR.
KEGG	bpt:Bpet1888.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EIDTYND.
Family and domain databases
HAMAP	MF_00210. [Tree]
InterPro	IPR016228. EPSP_synthase. IPR001986. EPSP_synthase_core. IPR006264. EPSP_synthase_subgroup. [Graphical view]
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
ProDom	PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01356. aroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROA_BORPD

Accession

Primary (citable) accession number: A9IJI7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 5, 2008
Last modified:	November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)