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A9IIC5

- PNCB_BORPD

UniProt

A9IIC5 - PNCB_BORPD

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, Bpet1730
Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciBPET340100:GJBO-1754-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:Bpet1730
OrganismiBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Taxonomic identifieri340100 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
ProteomesiUP000001225: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000129461Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi340100.Bpet1730.

Structurei

3D structure databases

ProteinModelPortaliA9IIC5.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

A9IIC5-1 [UniParc]FASTAAdd to Basket

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MIITSLLDTD LYKFSMMQVV LHHFPAAQVE YRYKCRTPGV NLRPYLDEIR    50
AEVHALCQLR FTEEELQYLG SLRFIKSDFV DFLGLFHLPE RCISIGEGEQ 100
PGEIAITVAG PWLHTILFEI PVLAIVNEVY FRNTRRHPDW DEGRQRLQSK 150
MHLVLDDPAL ADFRVAEYGT RRRFSKLWHE EIVSTMKAQM GAHFAGTSNV 200
LLAMRHNVLP LGTMGHEYLQ ACQALGPRLR DSQVFALEVW AKEYRGDLGI 250
ALSDVYGMDA FLRDFDMYFC KLFDGARHDS GDPFVWGERL LEHYRNNRVD 300
PRAKTLVFSD SLTFPRAIEL ARQFAGRCKV SFGIGTNLTN DLGHEPLQIV 350
MKMVRCNGQP VAKVSDAPEK TMCDDPAYLA YLRQVFQLPP A 391
Length:391
Mass (Da):44,836
Last modified:February 5, 2008 - v1
Checksum:iC0B0820213CBE36D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM902716 Genomic DNA. Translation: CAP42069.1.
RefSeqiWP_012248653.1. NC_010170.1.
YP_001630338.1. NC_010170.1.

Genome annotation databases

EnsemblBacteriaiCAP42069; CAP42069; Bpet1730.
GeneIDi5820936.
KEGGibpt:Bpet1730.
PATRICi21164907. VBIBorPet31633_1718.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM902716 Genomic DNA. Translation: CAP42069.1 .
RefSeqi WP_012248653.1. NC_010170.1.
YP_001630338.1. NC_010170.1.

3D structure databases

ProteinModelPortali A9IIC5.
ModBasei Search...

Protein-protein interaction databases

STRINGi 340100.Bpet1730.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP42069 ; CAP42069 ; Bpet1730 .
GeneIDi 5820936.
KEGGi bpt:Bpet1730.
PATRICi 21164907. VBIBorPet31633_1718.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci BPET340100:GJBO-1754-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-461 / DSM 12804 / CCUG 43448.

Entry informationi

Entry nameiPNCB_BORPD
AccessioniPrimary (citable) accession number: A9IIC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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