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Protein

Probable 5-dehydro-4-deoxyglucarate dehydratase

Gene

Bpet3876

Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2.UniRule annotation

Pathwayi: D-glucarate degradation

This protein is involved in step 2 of the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable 5-dehydro-4-deoxyglucarate dehydratase (Bpet3876)
This subpathway is part of the pathway D-glucarate degradation, which is itself part of Carbohydrate acid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate, the pathway D-glucarate degradation and in Carbohydrate acid metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciBPET340100:GJBO-3935-MONOMER.
UniPathwayiUPA00564; UER00628.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 5-dehydro-4-deoxyglucarate dehydrataseUniRule annotation (EC:4.2.1.41UniRule annotation)
Alternative name(s):
5-keto-4-deoxy-glucarate dehydrataseUniRule annotation
Short name:
KDGDHUniRule annotation
Gene namesi
Ordered Locus Names:Bpet3876
OrganismiBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Taxonomic identifieri340100 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001225 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 301301Probable 5-dehydro-4-deoxyglucarate dehydratasePRO_1000132268Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi340100.Bpet3876.

Structurei

3D structure databases

ProteinModelPortaliA9I3W2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DapA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105UVJ. Bacteria.
COG0329. LUCA.
HOGENOMiHOG000173605.
KOiK01707.
OMAiRNRKKGY.
OrthoDBiEOG6W7235.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00694. KDGDH.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
IPR017655. Dehydro-deoxyglucarate_dehyd.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
SMARTiSM01130. DHDPS. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03249. KdgD. 1 hit.

Sequencei

Sequence statusi: Complete.

A9I3W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPQELKARI ASGLLSFPVT HFNADFSLNL PSYQKHVAWL SGYDAAALFA
60 70 80 90 100
AGGTGELFSL TPQEIGEVTR AAKEAAGSVP IISGCGYGTE LAKDIARRAE
110 120 130 140 150
QAGADGLLLL PHYLMEVPQE GIYQHVKAVC DSTGLGVIVY NRSNSVANAD
160 170 180 190 200
TVARLADACP NLVGFKDGTG QTGLVRRITA KLGNRLSYIG GMPTHELFAQ
210 220 230 240 250
GFNGLGLSTY SSAVFNFVPE LALRFYKALK AGDEATMAQI LDSFFFPFAD
260 270 280 290 300
IRDREKGYAV SIIKAGVELI GHTPGPVRAP LTNLTPQEKD MLKALIANAG

S
Length:301
Mass (Da):31,984
Last modified:February 5, 2008 - v1
Checksum:i2835CA17DD586AEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM902716 Genomic DNA. Translation: CAP44221.1.

Genome annotation databases

EnsemblBacteriaiCAP44221; CAP44221; Bpet3876.
KEGGibpt:Bpet3876.
PATRICi21169359. VBIBorPet31633_3910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM902716 Genomic DNA. Translation: CAP44221.1.

3D structure databases

ProteinModelPortaliA9I3W2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi340100.Bpet3876.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP44221; CAP44221; Bpet3876.
KEGGibpt:Bpet3876.
PATRICi21169359. VBIBorPet31633_3910.

Phylogenomic databases

eggNOGiENOG4105UVJ. Bacteria.
COG0329. LUCA.
HOGENOMiHOG000173605.
KOiK01707.
OMAiRNRKKGY.
OrthoDBiEOG6W7235.

Enzyme and pathway databases

UniPathwayiUPA00564; UER00628.
BioCyciBPET340100:GJBO-3935-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00694. KDGDH.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
IPR017655. Dehydro-deoxyglucarate_dehyd.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
SMARTiSM01130. DHDPS. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03249. KdgD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-461 / DSM 12804 / CCUG 43448.

Entry informationi

Entry nameiKDGD_BORPD
AccessioniPrimary (citable) accession number: A9I3W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: May 11, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.