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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:Bpet0564
OrganismiBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Taxonomic identifieri340100 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001225 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000993161 – 277Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST277

Interactioni

Protein-protein interaction databases

STRINGi340100.Bpet0564.

Structurei

3D structure databases

ProteinModelPortaliA9I1T6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT. Bacteria.
COG0639. LUCA.
HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.
OrthoDBiPOG091H0691.

Family and domain databases

CDDicd07422. MPP_ApaH. 1 hit.
Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH. 1 hit.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.

Sequencei

Sequence statusi: Complete.

A9I1T6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGSIWMIGD VQGCCAPLEQ LLAHPDLAGD PDARFWFAGD LVNRGPQSLA
60 70 80 90 100
SLRRIIGLGE RAVAVLGNHD LHLLAAAAGV RKPSKSDTIG EILQAPDADD
110 120 130 140 150
LVDWLRHRPL AHFEQGHLLV HAGVLAKWDV AKTLALAGEV QEALRGPNWQ
160 170 180 190 200
KALQKMYGNE PVHWKEHHKG GKRMRVIINA LTRIRLCTPA GHMEFATKVP
210 220 230 240 250
PGAWPAGLMP WFDVPGRATR DITVVFGHWS TLGLLLRPDV ICLDTGCVWG
260 270
GSLSALRLQD RKLVQIKCSQ FQDPLAD
Length:277
Mass (Da):30,392
Last modified:February 5, 2008 - v1
Checksum:iE48D4D15DDB727BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM902716 Genomic DNA. Translation: CAP40896.1.

Genome annotation databases

EnsemblBacteriaiCAP40896; CAP40896; Bpet0564.
KEGGibpt:Bpet0564.
PATRICi21162585. VBIBorPet31633_0572.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM902716 Genomic DNA. Translation: CAP40896.1.

3D structure databases

ProteinModelPortaliA9I1T6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi340100.Bpet0564.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP40896; CAP40896; Bpet0564.
KEGGibpt:Bpet0564.
PATRICi21162585. VBIBorPet31633_0572.

Phylogenomic databases

eggNOGiENOG4105DDT. Bacteria.
COG0639. LUCA.
HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.
OrthoDBiPOG091H0691.

Family and domain databases

CDDicd07422. MPP_ApaH. 1 hit.
Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH. 1 hit.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAPAH_BORPD
AccessioniPrimary (citable) accession number: A9I1T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: November 30, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.