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A9HXK3 (UPPP_BORPD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Bpet3455
OrganismBordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) [Complete proteome] [HAMAP]
Taxonomic identifier340100 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 287287Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000197349

Regions

Transmembrane6 – 2621Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane204 – 22421Helical; Potential
Transmembrane238 – 25821Helical; Potential
Transmembrane265 – 28521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A9HXK3 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: D737037DE8DFC435

FASTA28731,035
        10         20         30         40         50         60 
MTDSTLYLIK AFFLGIIEGL TEFIPVSSTG HLILIGDWIN FTSSSGKVFE VVIQFGSILA 

        70         80         90        100        110        120 
VMWIFRARLW QLIRGTLTGV PAETAFTRNL LLAFLPAAVV GAIFIKTIKQ VFYHPGVVAV 

       130        140        150        160        170        180 
TLVLGGLIML WVERKTHHTP GDAPGAADDT ASDERASAHT LEQISWKQAL GVGVAQCLAM 

       190        200        210        220        230        240 
VPGTSRSGAT IIGGMIAGIQ RKTATEFSFF LAMPTMLGAA TYDLYRNIDL LSQHDLSAIA 

       250        260        270        280 
VGFAAAFISA LVVVRAVLRF VANHTYRGFA WYRIALGIVV AAWLMTK 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM902716 Genomic DNA. Translation: CAP43798.1.
RefSeqYP_001632066.1. NC_010170.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340100.Bpet3455.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP43798; CAP43798; Bpet3455.
GeneID5820354.
KEGGbpt:Bpet3455.
PATRIC21168505. VBIBorPet31633_3490.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAMGASKRS.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycBPET340100:GJBO-3505-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_BORPD
AccessionPrimary (citable) accession number: A9HXK3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families