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A9HKS8 (RNPA_GLUDA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component

Short name=RNase P protein
Short name=RNaseP protein
EC=3.1.26.5
Alternative name(s):
Protein C5
Gene names
Name:rnpA
Ordered Locus Names:GDI2137, Gdia_0356
OrganismGluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) [Complete proteome] [HAMAP]
Taxonomic identifier272568 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconacetobacter

Protein attributes

Sequence length116 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity. HAMAP-Rule MF_00227

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00227

Subunit structure

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Sequence similarities

Belongs to the RnpA family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

tRNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 116116Ribonuclease P protein component HAMAP-Rule MF_00227
PRO_1000100363

Sequences

Sequence LengthMass (Da)Tools
A9HKS8 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: C7F7D698F0D070D4

FASTA11612,878
        10         20         30         40         50         60 
MADRAHRLKK RAEFLKVASR GRKVPSPGLV LQALGRDDSD PARIGFTVTK KVGNAVVRNR 

        70         80         90        100        110 
TRRRLREAVR VVEREEPLNG VDLVLIGRDG TRGRTFAALV GDLRRTLRKA GVRGAE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001189 Genomic DNA. Translation: ACI50152.1.
AM889285 Genomic DNA. Translation: CAP56080.1.
RefSeqYP_001602382.1. NC_010125.1.
YP_002274767.1. NC_011365.1.

3D structure databases

ProteinModelPortalA9HKS8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272568.GDI_2137.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI50152; ACI50152; Gdia_0356.
CAP56080; CAP56080; GDI2137.
GeneID5792496.
6973750.
KEGGgdi:GDI_2137.
gdj:Gdia_0356.
PATRIC22049094. VBIGluDia203729_0363.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG284862.
HOGENOMHOG000266302.
KOK03536.
OMAQIHGERG.
OrthoDBEOG6T4S2H.

Enzyme and pathway databases

BioCycGDIA272568:GJPS-2176-MONOMER.

Family and domain databases

Gene3D3.30.230.10. 1 hit.
HAMAPMF_00227. RNase_P.
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view]
PfamPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54211. SSF54211. 1 hit.
TIGRFAMsTIGR00188. rnpA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNPA_GLUDA
AccessionPrimary (citable) accession number: A9HKS8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families