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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:GDI2137, Gdia_0356
OrganismiGluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)
Taxonomic identifieri272568 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconacetobacter
Proteomesi
  • UP000000736 Componenti: Chromosome
  • UP000001176 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001003631 – 116Ribonuclease P protein componentAdd BLAST116

Proteomic databases

PRIDEiA9HKS8.

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi272568.Gdia_0356.

Structurei

3D structure databases

ProteinModelPortaliA9HKS8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41087PG. Bacteria.
COG0594. LUCA.
HOGENOMiHOG000266302.
KOiK03536.
OMAiGHAGWDY.
OrthoDBiPOG091H01XK.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P. 1 hit.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomiPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.

Sequencei

Sequence statusi: Complete.

A9HKS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADRAHRLKK RAEFLKVASR GRKVPSPGLV LQALGRDDSD PARIGFTVTK
60 70 80 90 100
KVGNAVVRNR TRRRLREAVR VVEREEPLNG VDLVLIGRDG TRGRTFAALV
110
GDLRRTLRKA GVRGAE
Length:116
Mass (Da):12,878
Last modified:February 5, 2008 - v1
Checksum:iC7F7D698F0D070D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001189 Genomic DNA. Translation: ACI50152.1.
AM889285 Genomic DNA. Translation: CAP56080.1.
RefSeqiWP_012225945.1. NC_011365.1.

Genome annotation databases

EnsemblBacteriaiACI50152; ACI50152; Gdia_0356.
CAP56080; CAP56080; GDI2137.
KEGGigdi:GDI2137.
gdj:Gdia_0356.
PATRICi22049094. VBIGluDia203729_0363.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001189 Genomic DNA. Translation: ACI50152.1.
AM889285 Genomic DNA. Translation: CAP56080.1.
RefSeqiWP_012225945.1. NC_011365.1.

3D structure databases

ProteinModelPortaliA9HKS8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272568.Gdia_0356.

Proteomic databases

PRIDEiA9HKS8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI50152; ACI50152; Gdia_0356.
CAP56080; CAP56080; GDI2137.
KEGGigdi:GDI2137.
gdj:Gdia_0356.
PATRICi22049094. VBIGluDia203729_0363.

Phylogenomic databases

eggNOGiENOG41087PG. Bacteria.
COG0594. LUCA.
HOGENOMiHOG000266302.
KOiK03536.
OMAiGHAGWDY.
OrthoDBiPOG091H01XK.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P. 1 hit.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomiPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRNPA_GLUDA
AccessioniPrimary (citable) accession number: A9HKS8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.