A9HKQ2 (A9HKQ2_GLUDA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163

Gene names

Name:	def EMBL CAP56070.1
Synonyms:	def1 HAMAP MF_00163
Ordered Locus Names:	GDI2127, Gdia_0346

Organism

Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) [Complete proteome] [HAMAP]

Taxonomic identifier

272568 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconacetobacter

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. SAAS SAAS000181 HAMAP MF_00163
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. RuleBase RU003335 HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis SAAS SAAS000181 HAMAP MF_00163
Ligand	Iron HAMAP MF_00163 Metal-binding SAAS SAAS000181 HAMAP MF_00163
Molecular function	Hydrolase SAAS SAAS000181 HAMAP MF_00163 EMBL ACI50142.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	146	1	By similarity HAMAP MF_00163
	Metal binding	103	1	Iron By similarity HAMAP MF_00163
	Metal binding	145	1	Iron By similarity HAMAP MF_00163
	Metal binding	149	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	A9HKQ2 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 41AE0A3B2EDCC27C	FASTA	179	19,927
	10 20 30 40 50 60 MIDRDAIAAA IPMPILVAPQ AILRQKARPV RPEDAAGVRD ALPRMFAAMY QAPGIGLAAP 70 80 90 100 110 120 QVGMGLRFAI VDLGEEGERQ PLILINPDVI AESDSLASRE EGCLSLPNQY AEVIRPDRVR 130 140 150 160 170 VRYRTLDGTE EELEADGLLA TCIQHEIDHL EGILFVDHLS TLKRNMIMRR LAKEQRQKR

References

[1]

"Gluconacetobacter diazotrophicus Pal5 complete genome." Bertalan M., Baldani I.J., Ferreira P. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49037 / DSM 5601 / PAl5.

[2]

"Complete sequence of chromosome of Gluconacetobacter diazotrophicus PAl 5." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Triplett E.W. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49037 / DSM 5601 / PAl5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001189 Genomic DNA. Translation: ACI50142.1. AM889285 Genomic DNA. Translation: CAP56070.1.
RefSeq	YP_001602372.1. NC_010125.1. YP_002274757.1. NC_011365.1.
3D structure databases
ProteinModelPortal	A9HKQ2.
ModBase	Search...
Protein-protein interaction databases
STRING	A9HKQ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5792486. 6973740.
GenomeReviews	Gene locus GDI2127 in contig AM889285_GR. Gene locus Gdia_0346 in contig CP001189_GR.
KEGG	gdi:GDI_2127. gdj:Gdia_0346.
PATRIC	22049074. VBIGluDia203729_0353.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG665227.
OMA	KANGWLA.
ProtClustDB	CLSK936521.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9HKQ2_GLUDA

Accession

Primary (citable) accession number: A9HKQ2

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)