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A9HJG3 (A9HJG3_GLUDA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine synthase 2 HAMAP-Rule MF_00420

EC=6.3.5.3 HAMAP-Rule MF_00420
Alternative name(s):
Phosphoribosylformylglycinamidine synthase II HAMAP-Rule MF_00420
Gene names
Name:purL HAMAP-Rule MF_00420 EMBL CAP55903.1
Ordered Locus Names:GDI1960 EMBL CAP55903.1
OrganismGluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) [Complete proteome] [HAMAP] EMBL CAP55903.1
Taxonomic identifier272568 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconacetobacter

Protein attributes

Sequence length737 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. HAMAP-Rule MF_00420

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. HAMAP-Rule MF_00420

Subunit structure

Heterodimer of two subunits, PurQ and PurL By similarity. HAMAP-Rule MF_00420

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00420.

Sequence similarities

Belongs to the FGAMS family. HAMAP-Rule MF_00420

Ontologies

Keywords
   Biological processPurine biosynthesis HAMAP-Rule MF_00420
   Cellular componentCytoplasm HAMAP-Rule MF_00420
   LigandATP-binding HAMAP-Rule MF_00420
Nucleotide-binding
   Molecular functionLigase HAMAP-Rule MF_00420
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' IMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoribosylformylglycinamidine synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding108 – 11912ATP By similarity HAMAP-Rule MF_00420

Sequences

Sequence LengthMass (Da)Tools
A9HJG3 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: B2AC151E0A665F73

FASTA73777,704
        10         20         30         40         50         60 
MSSEKGQRPV DQDLAKEFGL TAEEYGNVLS IMGRTPSLTE LGIFSVMWSE HCSYKSSRVW 

        70         80         90        100        110        120 
LKTLPTTAPW VIHGPGENAG VVDIGQGLAA IFKMESHNHP SFIEPYQGAA TGVGGILRDV 

       130        140        150        160        170        180 
FTMGARPVAN LNALRFGSPE NPQTRRIVDG VVRGVGGYGN CVGVPTVGGE INFHPSYDGN 

       190        200        210        220        230        240 
PLVNAMTVGI ARQDRIFLSA AAGVGNPVIY VGSKTGRDGI HGATMSSSEF DEDALAKRPT 

       250        260        270        280        290        300 
VQVGDPFVEK LLIEACLELM ATDAIVAIQD MGAAGLTSSS VEMAGKGGVG IDLDLDAVPQ 

       310        320        330        340        350        360 
RERGMTAYEM MLSESQERML IVIRPDRTDV ARAIFEKWEL DFAVIGHLTE TGHIVVRHQG 

       370        380        390        400        410        420 
RVEADIPLDP LADQAPIYRR PTAPAPVPAP LGPLTDPVGI EQALIRLIGC PDLASRAWVW 

       430        440        450        460        470        480 
NQYDSTVGGQ TVKRPGGADA AIVKIEDTSL GLALTTDCTP RYCRADARLG GAQAVAEAWR 

       490        500        510        520        530        540 
NIVATGARPL AVTDNLNFGS PEKPEVMGQF VAAIEGMGEA CRALDFPVVS GNVSLYNETR 

       550        560        570        580        590        600 
APDGSSVSIL PTPAIGGLGV LEDVAKAVGL AMPADCTLVL VGATRGEMGQ SLWLREIHGR 

       610        620        630        640        650        660 
EDGPPPALDL AAERRNGDFV RGQIQDGHVV ACHDVADGGL LVTLAEMVMA GDVGCVLSAP 

       670        680        690        700        710        720 
QSGIRPEAFW FGEDQSRYVV AVRDADAFTL AATGAGVETR VLGRSGGDGL TLPSGATIST 

       730 
ARLNAVNSAF FPALMDR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM889285 Genomic DNA. Translation: CAP55903.1.
RefSeqYP_001602205.1. NC_010125.1.

3D structure databases

ProteinModelPortalA9HJG3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP55903; CAP55903; GDI1960.
GeneID5789312.
KEGGgdi:GDI_1960.
PATRIC22059468. VBIGluDia122154_1893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01952.
OMARDICGRE.
OrthoDBEOG6FNHHR.

Enzyme and pathway databases

BioCycGDIA272568:GJPS-1997-MONOMER.
UniPathwayUPA00074; UER00128.

Family and domain databases

Gene3D3.30.1330.10. 2 hits.
3.90.650.10. 1 hit.
HAMAPMF_00420. PurL_2.
InterProIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR010074. PRibForGlyAmidine_synth_II.
IPR016188. PurM_N-like.
[Graphical view]
PfamPF00586. AIRS. 2 hits.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMSSF55326. SSF55326. 2 hits.
SSF56042. SSF56042. 2 hits.
TIGRFAMsTIGR01736. FGAM_synth_II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA9HJG3_GLUDA
AccessionPrimary (citable) accession number: A9HJG3
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: June 11, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)