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Protein

Aldose 1-epimerase

Gene

galM

Organism
Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei221 – 2211Proton donorUniRule annotation
Binding sitei293 – 2931SubstrateUniRule annotation
Active sitei359 – 3591Proton acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciGDIA272568:GJPS-877-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:galMImported
Ordered Locus Names:GDI0866Imported, Gdia_1153Imported
OrganismiGluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)Imported
Taxonomic identifieri272568 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconacetobacter
Proteomesi
  • UP000000736 Componenti: Chromosome
  • UP000001176 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3232Sequence analysisAdd
BLAST
Chaini33 – 402370Aldose 1-epimeraseSequence analysisPRO_5006947460Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272568.Gdia_1153.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105ENN. Bacteria.
COG2017. LUCA.
HOGENOMiHOG000072798.
KOiK01785.
OMAiSPNHPDW.
OrthoDBiEOG69WFM5.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9HBF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRISPTRLA TSLLAATALV SATLASATPV RAADAPVALA RAGFGTMADG
60 70 80 90 100
KPVEILTLRN AHGVSVRFIT YGGIITAIDT PDRTGHTDDI VLGFPDLQGY
110 120 130 140 150
TVDSAQGGLF FGAMIGRYAN RIARGTFTLD GATYHVPVTA PPNALHGGTR
160 170 180 190 200
GFDKHLWTVD GTATDAHSAS ATLSLTSPDG DQGFPGTLKV SVTYTLDDQD
210 220 230 240 250
RLTLHYRATT DKPTVLNLTN HSYFNLGGEG SGSIEDEILQ INADHFTPTD
260 270 280 290 300
PTAIPTGDIA PVAGTPLDFR KPMRIGVHLR DSYPQLMFAR GYDHNWVVNG
310 320 330 340 350
PAGAAPRPAA HIVDPRTGRT MDVLTSQPGL QVYTSNSLDG AYAGVSHRAY
360 370 380 390 400
RQTDAIAFEA EHYPDSPNHP SFPTTTLRPG ETFDYTTIFH FGVQPAAPRH

GQ
Length:402
Mass (Da):42,845
Last modified:February 5, 2008 - v1
Checksum:iBFF0199FF0B8EB61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001189 Genomic DNA. Translation: ACI50936.1.
AM889285 Genomic DNA. Translation: CAP54809.1.
RefSeqiWP_012223648.1. NC_011365.1.

Genome annotation databases

EnsemblBacteriaiACI50936; ACI50936; Gdia_1153.
CAP54809; CAP54809; GDI0866.
KEGGigdi:GDI0866.
gdj:Gdia_1153.
PATRICi22050676. VBIGluDia203729_1144.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001189 Genomic DNA. Translation: ACI50936.1.
AM889285 Genomic DNA. Translation: CAP54809.1.
RefSeqiWP_012223648.1. NC_011365.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272568.Gdia_1153.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI50936; ACI50936; Gdia_1153.
CAP54809; CAP54809; GDI0866.
KEGGigdi:GDI0866.
gdj:Gdia_1153.
PATRICi22050676. VBIGluDia203729_1144.

Phylogenomic databases

eggNOGiENOG4105ENN. Bacteria.
COG2017. LUCA.
HOGENOMiHOG000072798.
KOiK01785.
OMAiSPNHPDW.
OrthoDBiEOG69WFM5.

Enzyme and pathway databases

UniPathwayiUPA00242.
BioCyciGDIA272568:GJPS-877-MONOMER.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the sugarcane nitrogen-fixing endophyte Gluconacetobacter diazotrophicus Pal5."
    Bertalan M., Albano R., Padua V., Rouws L., Rojas C., Hemerly A., Teixeira K., Schwab S., Araujo J., Oliveira A., Franca L., Magalhaes V., Alqueres S., Cardoso A., Almeida W., Loureiro M.M., Nogueira E., Cidade D.
    , Oliveira D., Simao T., Macedo J., Valadao A., Dreschsel M., Freitas F., Vidal M., Guedes H., Rodrigues E., Meneses C., Brioso P., Pozzer L., Figueiredo D., Montano H., Junior J., Filho G., Flores V., Ferreira B., Branco A., Gonzalez P., Guillobel H., Lemos M., Seibel L., Macedo J., Alves-Ferreira M., Sachetto-Martins G., Coelho A., Santos E., Amaral G., Neves A., Pacheco A.B., Carvalho D., Lery L., Bisch P., Rossle S.C., Urmenyi T., Kruger W.V., Martins O., Baldani J.I., Ferreira P.C.
    BMC Genomics 10:450-450(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49037 / DSM 5601 / PAl5Imported and PAl 5Imported.
  2. "Two genome sequences of the same bacterial strain, Gluconacetobacter diazotrophicus PAl 5, suggest a new standard in genome sequence submission."
    Giongo A., Tyler H.L., Zipperer U.N., Triplett E.W.
    Stand. Genomic Sci. 2:309-317(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49037 / DSM 5601 / PAl5Imported and PAl 5Imported.

Entry informationi

Entry nameiA9HBF6_GLUDA
AccessioniPrimary (citable) accession number: A9HBF6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 13, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.