A9HB20 (GLMM_GLUDA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	GDI0812, Gdia_1205

Organism

Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) [Complete proteome] [HAMAP]

Taxonomic identifier

272568 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconacetobacter

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 452	452	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000201105
Sites
	Active site	104	1	Phosphoserine intermediate By similarity
	Metal binding	104	1	Magnesium; via phosphate group By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
Amino acid modifications
	Modified residue	104	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9HB20 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 8E5A0D0D63B31511	FASTA	452	48,393
	10 20 30 40 50 60 MSKTRHLFGT DGIRGLANQD PMTVEIAQKL GQAAGLRFTR GVHRHRVLLG KDTRLSGYMI 70 80 90 100 110 120 ECALVSGFLS AGMDVTLVGP MPTPAIAMLT RSLRADLGVM ISASHNPFGD NGIKLFGPDG 130 140 150 160 170 180 FKLSDETEAE IEELMRSDLA GRLAAPDRIG RASRLNDAAG RYIENAKASF PRGRRLDGLR 190 200 210 220 230 240 IVIDCANGAA YRVAPTALWE LGAEVIRIGC EPDGININEQ CGSTKPESLC EAVVAHGAHI 250 260 270 280 290 300 GIALDGDADR VLIADEKGRL IDGDQILALI ARSWGRQGRL NSAQIVATVM SNMGLARCLE 310 320 330 340 350 360 GLGLELVRTA VGDRYVVERM RELGANLGGE QSGHMVLSDF ATTGDGLVAA LQVLAVLVEE 370 380 390 400 410 420 GRPASEVCRM FTPFPQMLRN VRFTGKSPLH APSVQDARRR AEAELGTAGR LLLRESGTEP 430 440 450 LVRVMAEAED PALVERIVAE MCEAIDSAQV VA

References

[1]

"Gluconacetobacter diazotrophicus Pal5 complete genome." Bertalan M., Baldani I.J., Ferreira P. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49037 / DSM 5601 / PAl5.

[2]

"Complete sequence of chromosome of Gluconacetobacter diazotrophicus PAl 5." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Triplett E.W. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49037 / DSM 5601 / PAl5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001189 Genomic DNA. Translation: ACI50988.1. AM889285 Genomic DNA. Translation: CAP54755.1.
RefSeq	YP_001601093.1. NC_010125.1. YP_002275603.1. NC_011365.1.
3D structure databases
ProteinModelPortal	A9HB20.
ModBase	Search...
Protein-protein interaction databases
STRING	A9HB20.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5789498. 6974609.
GenomeReviews	Gene locus GDI0812 in contig AM889285_GR. Gene locus Gdia_1205 in contig CP001189_GR.
KEGG	gdi:GDI_0812. gdj:Gdia_1205.
PATRIC	22050778. VBIGluDia203729_1195.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	LENTIPE.
ProtClustDB	PRK14315.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_GLUDA

Accession

Primary (citable) accession number: A9HB20

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program