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A9GU24 (DNLI_SORC5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA ligase

EC=6.5.1.1
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]
Gene names
Name:lig
Ordered Locus Names:sce6857
OrganismSorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) [Complete proteome] [HAMAP]
Taxonomic identifier448385 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesSorangiineaePolyangiaceaeSorangium

Protein attributes

Sequence length533 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 533533Probable DNA ligase HAMAP-Rule MF_00407
PRO_0000365239

Sites

Active site2131N6-AMP-lysine intermediate By similarity
Binding site2111ATP By similarity
Binding site2181ATP By similarity
Binding site2331ATP By similarity
Binding site2621ATP By similarity
Binding site3021ATP By similarity
Binding site3741ATP By similarity
Binding site3801ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A9GU24 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: A52A1D4621098BA1

FASTA53357,294
        10         20         30         40         50         60 
MLVSDLVATS ERVAALSRRV EKIGALAALL RRFSPAEVQI GVDWLTGRLR QGRLGLGPSV 

        70         80         90        100        110        120 
FAEARRASPS VAQPALTLGD ADAVFTEIAR ASGPGAGGER RAALAGLFAR ATDLERDFFA 

       130        140        150        160        170        180 
RLLAGELRQE RLEPVMVDAV ARAARVPPAS LRRAVMLAGD AAEVVKAALL EGALGLQRFS 

       190        200        210        220        230        240 
LQLLRPVQPM LAQSADDVVT ALSELRAMAL EWKLDGVRVQ AHKAGDEVRV FSRGLGPVTK 

       250        260        270        280        290        300 
AVPEIVEIVR ALPVRSVVLD GEALAFRPDG APHPFQVTMR RFGRAHDAAA LRAELPLRAL 

       310        320        330        340        350        360 
FFDVLHLDGE DLLDRPGSER TAALRQVLDR SLRVPRIELP TAAEAEAFFA DALAHGHEGV 

       370        380        390        400        410        420 
IAKSLAAPYE AGRRRGTWLK VKRARTLDLV VLAAEWGTGR RRGLLSNLHI GARDPAAGGF 

       430        440        450        460        470        480 
VLLGKTFKGM NDEVLAWQTQ RLLELEIGRD ADTVYVRPEI VVEVAFDGLQ SSPRYPGGVA 

       490        500        510        520        530 
LRSARVKRYR PDKPAGEIST MDEVRAIHAG ALAGEAAEKG QAEGGGEELE DDG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM746676 Genomic DNA. Translation: CAN97026.1.
RefSeqYP_001617506.1. NC_010162.1.

3D structure databases

ProteinModelPortalA9GU24.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING448385.sce6857.

Proteomic databases

PRIDEA9GU24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAN97026; CAN97026; sce6857.
GeneID5814087.
KEGGscl:sce6857.
PATRIC23672589. VBISorCel80414_7491.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1793.
HOGENOMHOG000036008.
KOK01971.
OMAIQSSPRY.
OrthoDBEOG6Q8HXT.

Enzyme and pathway databases

BioCycSCEL448385:GJ75-7107-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNLI_SORC5
AccessionPrimary (citable) accession number: A9GU24
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families