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A9GU20 (A9GU20_SORC5) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlB EMBL CAN97025.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:sce6856 EMBL CAN97025.1
OrganismSorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) [Complete proteome] [HAMAP] EMBL CAN97025.1
Taxonomic identifier448385 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesSorangiineaePolyangiaceaeSorangium

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011127

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS011127 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011127

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS011127 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011127.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011127

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain110 – 308199ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding139 – 19456ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2621Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
A9GU20 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 875AB6CFBF2477AA

FASTA34536,979
        10         20         30         40         50         60 
MVERQVRKRV GVVMGGSSGE RDVSLRSGAA VAEALEARGY DVVRITLGDR FGAELCATLQ 

        70         80         90        100        110        120 
RARLDAAFLA LHGRLGEDGC VQGVLELAQV PYTGSSVLAS ALAMDKLKAK EMFRLHNVPT 

       130        140        150        160        170        180 
PPYYTVGANQ DLEELDAVHG SFGFPVIVKP RGEGSSLGVT KAGSLEELKS ALALAFEFDD 

       190        200        210        220        230        240 
AAIVERFVAG TEVNVGILDG KVLGAIEIVP KKGLYDYEAK YTPGMTEYHM PARLPPTRYR 

       250        260        270        280        290        300 
GVLNLAERAA QALGCTGAVR VDLLVTGGEN EYVLEVNTLP GMTQTSLLPK IAEAAGYEFG 

       310        320        330        340 
DLCEAILASA RLHQPVRRRA PAASELRLSE RGQAEKRLRL VKSAI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM746676 Genomic DNA. Translation: CAN97025.1.
RefSeqYP_001617505.1. NC_010162.1.

3D structure databases

ProteinModelPortalA9GU20.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING448385.sce6856.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAN97025; CAN97025; sce6856.
GeneID5811347.
KEGGscl:sce6856.
PATRIC23672585. VBISorCel80414_7489.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMAWGEEREI.
OrthoDBEOG6ND0KB.
ProtClustDBCLSK2797976.

Enzyme and pathway databases

BioCycSCEL448385:GJ75-7106-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9GU20_SORC5
AccessionPrimary (citable) accession number: A9GU20
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)