A9GFJ0 (A9GFJ0_SORC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA mismatch repair protein MutH HAMAP-Rule MF_00759

Alternative name(s):
Methyl-directed mismatch repair protein HAMAP-Rule MF_00759

Gene names

Name:	mutH HAMAP-Rule MF_00759
Ordered Locus Names:	sce3003

Organism

Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) [Complete proteome] [HAMAP] EMBL CAN93162.1

Taxonomic identifier

448385 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Myxococcales › Sorangiineae › Polyangiaceae › Sorangium › Sorangium cellulosum

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair By similarity. HAMAP-Rule MF_00759
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00759.
Sequence similarities	Belongs to the MutH family. HAMAP-Rule MF_00759

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP-Rule MF_00759
Cellular component	Cytoplasm HAMAP-Rule MF_00759
Molecular function	Endonuclease HAMAP-Rule MF_00759 SAAS SAAS011337 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA modification Inferred from electronic annotation. Source: InterPro mismatch repair Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro endonuclease activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9GFJ0 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: C7552399F53B8D8A	FASTA	227	23,950
	10 20 30 40 50 60 MISALKPPRD EAELRCRAAA LAGLTLADLA RALGCAVPRG GVRTKGAAGA LVERALGATA 70 80 90 100 110 120 GSTSRPDFPH LGIELKTIPV EVTGAPQEST FVCSISLSDA DRAEWETSRA RAKLACVLWV 130 140 150 160 170 180 PIIAAPGRPS EERRLGAPRL WRPTDAQERV LRADFEDLMG LIGIGAVEAL TAHAGRWLQV 190 200 210 220 RPKAASGRSR TLAFGRDGEM IAALPRGFYL RPSFTGAILG DPAAIPA

References

[1]

"Complete genome sequence of the myxobacterium Sorangium cellulosum." Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O., Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J., Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A. , Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C., Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T., Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S., Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F., Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G., Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D., Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H., Puehler A., Mueller R. Nat. Biotechnol. 25:1281-1289(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: So ce56.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM746676 Genomic DNA. Translation: CAN93162.1.
RefSeq	YP_001613642.1. NC_010162.1.
3D structure databases
ProteinModelPortal	A9GFJ0.
ModBase	Search...
Protein-protein interaction databases
STRING	448385.sce3003.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAN93162; CAN93162; sce3003.
GeneID	5808146.
KEGG	scl:sce3003.
PATRIC	23664127. VBISorCel80414_3276.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3066.
HOGENOM	HOG000271839.
KO	K03573.
OMA	LRPKGAN.
ProtClustDB	PRK05070.
Enzyme and pathway databases
BioCyc	SCEL448385:GJ75-3119-MONOMER.
Family and domain databases
Gene3D	3.40.600.10. 1 hit.
HAMAP	MF_00759. MutH.
InterPro	IPR004230. DNA_mismatch_repair_MutH. IPR011337. DNA_rep_MutH/RE_typeII. IPR011335. Restrct_endonuc-II-like. [Graphical view]
Pfam	PF02976. MutH. 1 hit. [Graphical view]
SMART	SM00927. MutH. 1 hit. [Graphical view]
SUPFAM	SSF52980. Restrict_endonuc_II-like_core. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9GFJ0_SORC5

Accession

Primary (citable) accession number: A9GFJ0

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)