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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease
Biological processDNA damage, DNA repairUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotationImported
Ordered Locus Names:sce3003Imported
OrganismiSorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))Imported
Taxonomic identifieri448385 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesSorangiineaePolyangiaceaeSorangium
Proteomesi
  • UP000002139 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi448385.sce3003.

Structurei

3D structure databases

ProteinModelPortaliA9GFJ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 154MutHInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the MutH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105IRT. Bacteria.
COG3066. LUCA.
HOGENOMiHOG000271839.
KOiK03573.
OMAiPPDLKRD.
OrthoDBiPOG091H04RA.

Family and domain databases

Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH. 1 hit.
InterProiView protein in InterPro
IPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
PfamiView protein in Pfam
PF02976. MutH. 1 hit.
SMARTiView protein in SMART
SM00927. MutH. 1 hit.
SUPFAMiSSF52980. SSF52980. 1 hit.

Sequencei

Sequence statusi: Complete.

A9GFJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISALKPPRD EAELRCRAAA LAGLTLADLA RALGCAVPRG GVRTKGAAGA
60 70 80 90 100
LVERALGATA GSTSRPDFPH LGIELKTIPV EVTGAPQEST FVCSISLSDA
110 120 130 140 150
DRAEWETSRA RAKLACVLWV PIIAAPGRPS EERRLGAPRL WRPTDAQERV
160 170 180 190 200
LRADFEDLMG LIGIGAVEAL TAHAGRWLQV RPKAASGRSR TLAFGRDGEM
210 220
IAALPRGFYL RPSFTGAILG DPAAIPA
Length:227
Mass (Da):23,950
Last modified:February 5, 2008 - v1
Checksum:iC7552399F53B8D8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM746676 Genomic DNA. Translation: CAN93162.1.

Genome annotation databases

EnsemblBacteriaiCAN93162; CAN93162; sce3003.
KEGGiscl:sce3003.

Similar proteinsi

Entry informationi

Entry nameiA9GFJ0_SORC5
AccessioniPrimary (citable) accession number: A9GFJ0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 27, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported