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A9GC83 (UPPP_SORC5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:sce5989
OrganismSorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) [Complete proteome] [HAMAP]
Taxonomic identifier448385 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesSorangiineaePolyangiaceaeSorangium

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000083991

Regions

Transmembrane40 – 6021Helical; Potential
Transmembrane79 – 9921Helical; Potential
Transmembrane107 – 12721Helical; Potential
Transmembrane183 – 20321Helical; Potential
Transmembrane219 – 23921Helical; Potential
Transmembrane249 – 26921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A9GC83 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: D722BB967995E62D

FASTA30732,232
        10         20         30         40         50         60 
MFWFDAVLLG VLEGLTEFLP VSSTGHLILL GAWLGHQSEA AKTLDIVIQL GAVLAVVVYF 

        70         80         90        100        110        120 
RERLSTTVRG MVRRDPDSLR LALALAFAFL PAAVVGLLFH KAIKAHLFGP GPVAAALIVG 

       130        140        150        160        170        180 
GFLMIGVESL RRRRPDQGAP RVEDVTFQRA LAIGFAQCFS LWPGASRSMT TIVGGQLSGL 

       190        200        210        220        230        240 
STAAAAEFSF LLAIPTLGAA TVFDLVKNGR ALLDAPGGIV ALVVGLAVSF AVALLVIAVF 

       250        260        270        280        290        300 
LRYLKRYGLA PFGWYRIALG ALVLWLWIAS RSAPAEAGAA SASPAPRGDV AAAVDGLART 


GDHPSRP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM746676 Genomic DNA. Translation: CAN96153.1.
RefSeqYP_001616633.1. NC_010162.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING448385.sce5989.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAN96153; CAN96153; sce5989.
GeneID5804631.
KEGGscl:sce5989.
PATRIC23670721. VBISorCel80414_6550.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycSCEL448385:GJ75-6205-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SORC5
AccessionPrimary (citable) accession number: A9GC83
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families