Translation initiation factor IF-2 - Sorangium cellulosum (strain So ce56)

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A9G888 (A9G888_SORC5) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 39. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-2 HAMAP-Rule MF_00100 RuleBase RU000644

Gene names

Name:	infB HAMAP-Rule MF_00100
Ordered Locus Names:	sce5798

Organism

Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) [Complete proteome] [HAMAP] EMBL CAN95961.1

Taxonomic identifier

448385 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Sorangiineae › Polyangiaceae › Sorangium ›

Protein attributes

Sequence length	624 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity. HAMAP-Rule MF_00100 RuleBase RU000644
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00100 RuleBase RU000645.
Sequence similarities	Belongs to the IF-2 family. HAMAP-Rule MF_00100 RuleBase RU000644

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00100
Ligand	GTP-binding HAMAP-Rule MF_00100 RuleBase RU000323 Nucleotide-binding
Molecular function	Initiation factor HAMAP-Rule MF_00100 RuleBase RU000644 EMBL CAN95961.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: HAMAP translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

133 – 140

GTP By similarity HAMAP-Rule MF_00100

Nucleotide binding

179 – 183

GTP By similarity HAMAP-Rule MF_00100

Nucleotide binding

233 – 236

GTP By similarity HAMAP-Rule MF_00100

Region

127 – 275

149

G-domain By similarity HAMAP-Rule MF_00100

Sequences

Sequence

Length

Mass (Da)

Tools

A9G888 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: F9F2CAF63126A6C0
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FASTA

624

66,322

        10         20         30         40         50         60 
MGGRNTRPGT FGRQRPGGGG GLPRKPVQVS TQEMASHKKV IKIEEQVTLQ QLAAKMSLKA 

        70         80         90        100        110        120 
TDVLMRLLSM GMTGVNINST LDAETAKILA SEFGWSVEDV AVSEQDTLTA AMQAGADTDE 

       130        140        150        160        170        180 
DVEIRPPIVT VMGHVDHGKT SLLDRIRKAT VAEGEAGGIT QHIGAYRVET PRGTIAFLDT 

       190        200        210        220        230        240 
PGHEAFTAMR ARGASLTDIV ILVVAADDGV MPQTKEAISH AQAAKVPIIV AVNKIDKPGA 

       250        260        270        280        290        300 
DADKIKRDLA ALGLQPEEWG GETMFCAVSA KMGQGIDQLL ESVLLLAEVQ DLRANPKKRA 

       310        320        330        340        350        360 
SGTVIEALLD RGRGPVARVM VQDGTLRTGD ILLAGAAWGK VRAMTDELGR SVAEAGPATP 

       370        380        390        400        410        420 
VEVLGLNEVP SAGDPVHAVK DGKTAEEIAE TRRKKASKTL IPQDSRVSLE SITKNLQEAD 

       430        440        450        460        470        480 
QLELKLIIKG DVQGSVEAIT HALAKLSTEK VKVTIVNGAV GGITEGDVNL AVASKAIIVG 

       490        500        510        520        530        540 
FNVRPAGKAG ALAENEGVEI RLYNIIYNAV DDIRSAMEGL LPATKVEKVL GRAEVRQVFK 

       550        560        570        580        590        600 
ITKAGTVAGC MAISGSVKRT GEARLIRDNA VVWTGRLSGL RRFKDDVKEV VEGFECGISL 

       610        620 
DGYSDIKERD IIESFEIEEV KTKL

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References

[1]

"Complete genome sequence of the myxobacterium Sorangium cellulosum."
Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O., Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J., Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A.

Mueller R.
Nat. Biotechnol. 25:1281-1289(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: So ce56.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM746676 Genomic DNA. Translation: CAN95961.1.
RefSeq	YP_001616441.1. NC_010162.1.
3D structure databases
ProteinModelPortal	A9G888.
ModBase	Search...
Protein-protein interaction databases
STRING	448385.sce5798.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAN95961; CAN95961; sce5798.
GeneID	5805711.
KEGG	scl:sce5798.
PATRIC	23670297. VBISorCel80414_6337.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0532.
HOGENOM	HOG000076906.
KO	K02519.
OMA	NISREVI.
Enzyme and pathway databases
BioCyc	SCEL448385:GJ75-6009-MONOMER.
Family and domain databases
Gene3D	3.40.50.10050. 1 hit.
HAMAP	MF_00100_B. IF_2_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR006847. IF2_N. IPR005225. Small_GTP-bd_dom. IPR000178. TF_IF2_bacterial-like. IPR015760. TIF_IF2. IPR023115. TIF_IF2_dom3. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
PANTHER	PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF11987. IF-2. 1 hit. PF04760. IF2_N. 1 hit. [Graphical view]
SUPFAM	SSF52156. TIF_IF2_dom3. 1 hit. SSF50447. Translat_factor. 2 hits.
TIGRFAMs	TIGR00487. IF-2. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS01176. IF2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9G888_SORC5

Accession

Primary (citable) accession number: A9G888

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information