A9G862 (GLMM_SORC5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	sce5789

Organism

Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) [Complete proteome] [HAMAP]

Taxonomic identifier

448385 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Sorangiineae › Polyangiaceae › Sorangium

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 480	480	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000343601
Sites
	Active site	127	1	Phosphoserine intermediate By similarity
	Metal binding	127	1	Magnesium; via phosphate group By similarity
	Metal binding	269	1	Magnesium By similarity
	Metal binding	271	1	Magnesium By similarity
	Metal binding	273	1	Magnesium By similarity
Amino acid modifications
	Modified residue	127	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9G862 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: A374E876E9D7D17D	FASTA	480	51,042
	10 20 30 40 50 60 MPKHTKKDPR EGAPSATGEP QKQAAGRKLF GTDGVRGVAN QPPMTPEMAL RLGRAIAFVA 70 80 90 100 110 120 SHGKSRQVRV VIGKDTRLSG YMLETAIASG VCAMGGRVML SGPIPTPAVA QLTQSMRADA 130 140 150 160 170 180 GVVISASHNP YQDNGIKIFG PDGYKLPDTA EEEIERLMES HELDEARVVG AAIGSAVKLD 190 200 210 220 230 240 DARGRYVVFC KNTFPTALSL DGVKIVVDAA HGAAYRVAPS VFTELGANVT ALGVKPNGRN 250 260 270 280 290 300 INRETGALHP EHVKAEVLKR GAAIGIALDG DADRVIMVDE RGEVVDGDAI MALCALRMLR 310 320 330 340 350 360 TGKLPRNTIV TTVMSNLGLE RALKAQSGHV VRTAVGDRYV VEAMRNGGYS FGGEQSGHLI 370 380 390 400 410 420 FLDHATTGDG IVAALQVLAI MMEEDKPLSE LASKAMQRVP QVLENATFAT RLPLDSMQRT 430 440 450 460 470 480 RVTVDRIEKT LGDKGRILVR WSGTEPKLRV MVEGEDASTI GAYALEIIEA AKQDVAGASA

References

[1]

"Complete genome sequence of the myxobacterium Sorangium cellulosum." Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O., Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J., Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A. , Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C., Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T., Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S., Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F., Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G., Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D., Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H., Puehler A., Mueller R. Nat. Biotechnol. 25:1281-1289(2007) [PubMed: 17965706] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: So ce56.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM746676 Genomic DNA. Translation: CAN95952.1.
RefSeq	YP_001616432.1. NC_010162.1.
3D structure databases
ProteinModelPortal	A9G862.
ModBase	Search...
Protein-protein interaction databases
STRING	A9G862.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5810406.
GenomeReviews	Gene locus sce5789 in contig AM746676_GR.
KEGG	scl:sce5789.
PATRIC	23670277. VBISorCel80414_6327.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	IGSAKRI.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_SORC5

Accession

Primary (citable) accession number: A9G862

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program