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Protein

30S ribosomal protein S12

Gene

rpsL

Organism
Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

With S4 and S5 plays an important role in translational accuracy.UniRule annotation
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12UniRule annotation
Gene namesi
Name:rpsLUniRule annotation
Ordered Locus Names:sce0838
OrganismiSorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))
Taxonomic identifieri448385 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesSorangiineaePolyangiaceaeSorangium
Proteomesi
  • UP000002139 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000804181 – 13230S ribosomal protein S12Add BLAST132

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei893-methylthioaspartic acidBy similarity1

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiA9ETB7.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.UniRule annotation

Protein-protein interaction databases

STRINGi448385.sce0838.

Structurei

3D structure databases

ProteinModelPortaliA9ETB7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uS12 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UKE. Bacteria.
COG0048. LUCA.
HOGENOMiHOG000040063.
KOiK02950.
OMAiKRGVCTA.
OrthoDBiPOG091H025P.

Family and domain databases

CDDicd03368. Ribosomal_S12. 1 hit.
HAMAPiMF_00403_B. Ribosomal_S12_B. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiView protein in Pfam
PF00164. Ribosom_S12_S23. 1 hit.
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00055. RIBOSOMAL_S12. 1 hit.

Sequencei

Sequence statusi: Complete.

A9ETB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTISQLIRQ GREAARYKTA SPALKSCPQR RGVCVRVYTT TPKKPNSALR
60 70 80 90 100
KVCRVRLSNQ MEVTSYIPGE GHNLQEHSVV LIRGGRVKDL PGVRYHVVRG
110 120 130
TLDASGAAGP SSTNKATRNR KRSKYGVKRP KA
Length:132
Mass (Da):14,567
Last modified:February 5, 2008 - v1
Checksum:i719D52493570B703
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM746676 Genomic DNA. Translation: CAN90995.1.
RefSeqiWP_012233473.1. NC_010162.1.

Genome annotation databases

EnsemblBacteriaiCAN90995; CAN90995; sce0838.
KEGGiscl:sce0838.

Similar proteinsi

Entry informationi

Entry nameiRS12_SORC5
AccessioniPrimary (citable) accession number: A9ETB7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: June 7, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families