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Protein

Probable glutamine--tRNA ligase

Gene

EBI_22570

Organism
Enterocytozoon bieneusi (strain H348) (Microsporidian parasite)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei229L-glutamineBy similarity1
Binding sitei381L-glutamineBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi197 – 199ATPBy similarity3
Nucleotide bindingi203 – 209ATPBy similarity7
Nucleotide bindingi429 – 430ATPBy similarity2
Nucleotide bindingi437 – 439ATPBy similarity3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18By similarity)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
ORF Names:EBI_22570
OrganismiEnterocytozoon bieneusi (strain H348) (Microsporidian parasite)
Taxonomic identifieri481877 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaEnterocytozoonidaeEnterocytozoon
Proteomesi
  • UP000001742 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiMicrosporidiaDB:EBI_22570.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003883821 – 691Probable glutamine--tRNA ligaseAdd BLAST691

Structurei

3D structure databases

ProteinModelPortaliA9CSU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi196 – 206"HIGH" regionBy similarityAdd BLAST11
Motifi436 – 440"KMSKS" regionBy similarity5

Sequence similaritiesi

Phylogenomic databases

InParanoidiA9CSU5.
OrthoDBiEOG092C0PFH.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A9CSU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLDDKLRGI SLSDEKINEL KTKPNLIKNM EVIVNTGNNF TKMQYSLACI
60 70 80 90 100
APKNCNLIEL SNLIEEGYVT NDSLLKGLVK LGKKSKDEYI DFCKKHTYNE
110 120 130 140 150
QDIINFIRLL KEKKETKATI SSKLKEQYLY YDTKIFLKEM ENYNLNVPME
160 170 180 190 200
KYTKNWLDEG EIKFLHKPGE NPQKTKKIME DHLKRTGGKV ITRFPPEPNG
210 220 230 240 250
NLHIGHAKAL NLSFEYAKKF NGITYLRFDD TNPKNESNEL YNGIIEDVKW
260 270 280 290 300
LGFEPYAITA SSDHFEAMHE MAKTLIKKNK SYVCFCSLEE IRARRSKYQK
310 320 330 340 350
ERDEGNDDPL ILSPYRNTSV EQNLIEFEKM LKGEYKDGEA VLRFKMPLKS
360 370 380 390 400
KNPLMLDLVG ARIINMVHDR KQKNYIVYPS YEFALCVCDS LEDITHSFCS
410 420 430 440 450
REFYTRQEPY HWLLQELDMY EPVQWEFSRL NISNTVLSKR KLTKIVDEGL
460 470 480 490 500
NWDDPRFYTI KGMRRRGFPA SAINKFVQSV GITFSETIID VKILESFVLK
510 520 530 540 550
ELMQIAKKAT CIINPLKVYI NKCTTGIISN EPVDVNNIIY IDKDDFDETN
560 570 580 590 600
NSDFLRLTKI QPVGLINLGV LKYIKDESDG IRCELLTVDE CKPNKFIQWL
610 620 630 640 650
PNLDNKVELR MYKPLFKSFD PDEIGYMNDI DLTNSLEIID GYVDNTVLNT
660 670 680 690
HIEDKFQFIR IGFFCCDFDS IINDNQKKLV FNLTLPLNKN Y
Length:691
Mass (Da):80,660
Last modified:February 5, 2008 - v1
Checksum:i1F11DE3091ADF9CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGB01000003 Genomic DNA. Translation: EDQ31158.1.
RefSeqiXP_001827993.1. XM_001827941.1.

Genome annotation databases

EnsemblFungiiEDQ31158; EDQ31158; EBI_22570.
GeneIDi6004333.

Similar proteinsi

Entry informationi

Entry nameiSYQ_ENTBH
AccessioniPrimary (citable) accession number: A9CSU5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: February 5, 2008
Last modified: August 30, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families