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A9CMC8 (A9CMC8_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length1929 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 1 family. RuleBase RU003690

Sequences

Sequence LengthMass (Da)Tools
A9CMC8 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 61735EC3BF194880

FASTA1,929217,609
        10         20         30         40         50         60 
MELPWTALFL STVLLGLSCQ GSDWESDRNF ISAAGPLTND LVLNLNYPPG KQGSDVVSGN 

        70         80         90        100        110        120 
TDIYICQQPL PSFLSQYFSS LRASQVTHYK VLLSWAQLLP TGSSKNPDQE AVQCYRQLLQ 

       130        140        150        160        170        180 
SLKDAQLEPM VVLCHQTPPT SSAIQREGAF ADLFADYATL AFQSFGDLVE IWFTFSDLEK 

       190        200        210        220        230        240 
VIMDLPHKDL KASALQTLSN AHRRAFDIYH RKFSSQGGKL SVVLKAEDIP ELLPDPALAA 

       250        260        270        280        290        300 
LVQGSVDFLS LDLSYECQSV ATLPQKLSEL QNLEPKVKVF IYTLKLEDCP ATGTSPSSLL 

       310        320        330        340        350        360 
ISLLEAINKD QIQTVGFDVN AFLSCTSNSE ESPSCSLTDS LALQTEQQQE TAVPSSPGSA 

       370        380        390        400        410        420 
YQRVWAAFAN QSREERDAFL QDVFPEGFLW GISTGAFNVE GGWAEGGRGP SIWDHYGNLN 

       430        440        450        460        470        480 
AAEGQATAKV ASDSYHKPAS DVALLRGIRA QVYKFSISWS RLFPTGQKST PNRQGVAYYN 

       490        500        510        520        530        540 
KLIDRLLDSH IEPMATLFHW DLPQALQEQG GWQNESVVEA FLDYAAFCFS TFGDRVKLWV 

       550        560        570        580        590        600 
TFHEPWVMSY AGYGTGQHAP AISDPGMASF KVAHLILKAH ARTWHLYDLH HRLQQQGRVG 

       610        620        630        640        650        660 
IVLNSDWAEP LDRKSPQDLA AAERFLHFML GWFAHPIFVD GDYPTTLRAQ IQHINQQCGH 

       670        680        690        700        710        720 
PLAQLPEFTE AEKRLLKGSA DFLGLSHYTS RLISKAGRQT CTSSYDNIGG FSQHVDPEWP 

       730        740        750        760        770        780 
QTASPWIRVV PWGIRRLLRF ASMEYTKGKL PIFLAGNGMP VGEEADLFDD SVRVNYFNLY 

       790        800        810        820        830        840 
INEVLKAVKE DLVDVRSYIV RSLIDGYEGP LGFSQRFGLY HVNFNDSSRP RTPRKSAYFF 

       850        860        870        880        890        900 
TSIIEKNGFS AKKVKRNPLP VRADFTSRAR VTDSLPSEVP SKAKIVWEKF SKQPRFERDL 

       910        920        930        940        950        960 
FYHGTFRDDF LWGVSSSAYQ IEGGWNADGK GPSIWDNFTH TPGNGVKDNA TGDVACDSYH 

       970        980        990       1000       1010       1020 
QLDADLNILR TLKVKSYRFS ISWSRIFPTG RNSTINKQGV DYYNRLIDSL VDNNIFPMVT 

      1030       1040       1050       1060       1070       1080 
LFHWDLPQAL QDIGGWENPS LIELFDSYAD FCFKTFGDRV KFWMTFNEPW CHVVLGYSSG 

      1090       1100       1110       1120       1130       1140 
IFPPSVQEPG WLPYKVSHIV IKAHARVYHT YDEKYRSEQK GVISLSLNTH WAEPKDPGLQ 

      1150       1160       1170       1180       1190       1200 
RDVEAADRML QFTMGWFAHP IFKNGDYPDV MKWTVGNRSE LQHLASSRLP TFTEEEKNYV 

      1210       1220       1230       1240       1250       1260 
RGTADVFCIN TYTSVFVQHS TPRLNPPSYD DDMELKLIEM NSSTGVMHPD VPWGTRRLLN 

      1270       1280       1290       1300       1310       1320 
WIKEEYGNIP IYITENGQGL ENPTLDDTER IFYHKTYINE ALKAYKLDGV DLRGYSAWTL 

      1330       1340       1350       1360       1370       1380 
MDDFEWLLGY TMRFGLYHVD FNHVSRPRTA RASARYYAEV IANNGMPLAR EDEFLYGEFP 

      1390       1400       1410       1420       1430       1440 
KGFIWSAASA SYQVEGAWRA DGKGLSIWDT FSHTPLRIGN DDNGDVACDS YHKIAEDVVA 

      1450       1460       1470       1480       1490       1500 
LQNLGVSHYR FSIAWSRILP DGTTKFINEA GLSYYVRFID ALLAAGITPQ VTIYHWDLPQ 

      1510       1520       1530       1540       1550       1560 
ALQDVGGWEN ETIVQRFKEY ADVLFQRLGD RVKFWITLNE PFVIAAQGYG TGVSAPGISF 

      1570       1580       1590       1600       1610       1620 
RPGTAPYIAG HNLIKAHAEA WHLYNDVYRA RQGGTISITI SSDWAEPRDP TNQGDVEAAR 

      1630       1640       1650       1660       1670       1680 
RYVQFMGGWF AHPIFKNGDY PEVMKTRIRD RSLAAGLNKS RLPEFTESEK SRIKGTFDFF 

      1690       1700       1710       1720       1730       1740 
GFNHYTTVLA YNLDYPAAFS SFDADRGVAS IADSSWPVSG SFWLKVTPFG FRRILNWLKE 

      1750       1760       1770       1780       1790       1800 
EYNNPPIYVT ENGVSRRGEP ELNDTDRIYY LRSYINEALK AVQDKVDLRG YTVWSIMDNF 

      1810       1820       1830       1840       1850       1860 
EWATGFAERF GVHFVNRSDP SLPRIPKASA KFYATIVRCN GFPDPAQGPH PCLQQPEDAA 

      1870       1880       1890       1900       1910       1920 
PTASPVQSEV PFLGLMLGIA EAQTALYVLF ALLLLGACSL AFLTYKYCRR SKQGNAQPSQ 


HQLSPISSF 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000004908.
[2]"Actin-related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats."
Akiyama K., Morita H., Suetsugu S., Kuraba S., Numata Y., Yamamoto Y., Inui K., Ideura T., Wakisaka N., Nakano K., Oniki H., Takenawa T., Matsuyama M., Yoshimura A.
Mamm. Genome 19:41-50(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BUF/Mna EMBL BAF94253.1.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000004908.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABR06074532 Genomic DNA. No translation available.
AABR06074533 Genomic DNA. No translation available.
AABR06074534 Genomic DNA. No translation available.
AB294578 Genomic DNA. Translation: BAF94253.1.
RefSeqNP_446293.1. NM_053841.1.
UniGeneRn.92376.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000004908; ENSRNOP00000004908; ENSRNOG00000003681.
GeneID116569.
KEGGrno:116569.

Organism-specific databases

CTD3938.
RGD620823. Lct.

Phylogenomic databases

GeneTreeENSGT00550000074452.
HOVERGENHBG006290.
KOK01229.
OMAFADYATF.
OrthoDBEOG7MH0XV.
TreeFamTF314803.

Gene expression databases

GenevestigatorA9CMC8.

Family and domain databases

Gene3D3.20.20.80. 4 hits.
InterProIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 4 hits.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 4 hits.
PROSITEPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio619255.
PROA9CMC8.

Entry information

Entry nameA9CMC8_RAT
AccessionPrimary (citable) accession number: A9CMC8
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)