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Protein
Submitted name:

3-oxoacyl-(Acyl-carrier-protein) reductase

Gene

fabG

Organism
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431NADP; via amide nitrogenCombined sources
Binding sitei47 – 471NADPCombined sources
Binding sitei159 – 1591NADPCombined sources
Binding sitei163 – 1631NADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 236NADPCombined sources
Nucleotide bindingi68 – 692NADPCombined sources
Nucleotide bindingi94 – 963NADPCombined sources
Nucleotide bindingi192 – 1965NADPCombined sources

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. oxidoreductase activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciAGRO:ATU5465-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
3-oxoacyl-(Acyl-carrier-protein) reductaseImported
Gene namesi
Name:fabGImported
Ordered Locus Names:Atu5465Imported
Encoded oniPlasmid AtImported
OrganismiAgrobacterium tumefaciens (strain C58 / ATCC 33970)Imported
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
ProteomesiUP000000813 Componenti: Plasmid At

Interactioni

Protein-protein interaction databases

STRINGi176299.Atu5465.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IMRX-ray1.96A/B1-253[»]
ProteinModelPortaliA9CL57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1028.
OMAiAGRPEEM.
OrthoDBiEOG6N3CR8.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.

Sequencei

Sequence statusi: Complete.

A9CL57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLETIFGLR GRTALVTGSS RGIGAAIAEG LAGAGAHVIL HGVKPGSTAA
60 70 80 90 100
VQQRIIASGG TAQELAGDLS EAGAGTDLIE RAEAIAPVDI LVINASAQIN
110 120 130 140 150
ATLSALTPND LAFQLAVNLG STVDMLQSAL PKMVARKWGR VVSIGSINQL
160 170 180 190 200
RPKSVVTAYA ATKAAQHNLI QSQARDFAGD NVLLNTLAPG LVDTDRNADR
210 220 230 240 250
RAQDPEGWDE YVRTLNWMGR AGRPEEMVGA ALFLASEACS FMTGETIFLT

GGY
Length:253
Mass (Da):26,382
Last modified:January 15, 2008 - v1
Checksum:i83F37E15C3C0C114
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007872 Genomic DNA. Translation: AAK90840.1.
PIRiAB3217.
RefSeqiNP_396399.1. NC_003064.2.

Genome annotation databases

EnsemblBacteriaiAAK90840; AAK90840; Atu5465.
GeneIDi1137238.
KEGGiatu:Atu5465.
PATRICi20820085. VBIAgrTum91616_5137.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007872 Genomic DNA. Translation: AAK90840.1.
PIRiAB3217.
RefSeqiNP_396399.1. NC_003064.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IMRX-ray1.96A/B1-253[»]
ProteinModelPortaliA9CL57.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi176299.Atu5465.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK90840; AAK90840; Atu5465.
GeneIDi1137238.
KEGGiatu:Atu5465.
PATRICi20820085. VBIAgrTum91616_5137.

Phylogenomic databases

eggNOGiCOG1028.
OMAiAGRPEEM.
OrthoDBiEOG6N3CR8.

Enzyme and pathway databases

BioCyciAGRO:ATU5465-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C58 / ATCC 33970Imported.
  2. "Crystal Structure of 3-Oxoacyl (Acyl-Carrier-Protein) Reductase Atu5465 from Agrobacterium Tumefaciens."
    Patskovsky Y., Toro R., Bhosle R., Hillerich B., Seidel R.D., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Zencheck W.D., Imker H.J., Al Obaidi N.F., Stead M., Love J., Gerlt J.A., Almo S.C.
    Submitted (JAN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.96 ANGSTROMS) IN COMPLEX WITH NADP.

Entry informationi

Entry nameiA9CL57_AGRT5
AccessioniPrimary (citable) accession number: A9CL57
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 7, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, PlasmidImported, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.