A9C391 (A9C391_DELAS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Amino-acid acetyltransferase HAMAP MF_01105
EC=2.3.1.1 HAMAP MF_01105

Alternative name(s):
N-acetylglutamate synthase HAMAP MF_01105

Gene names

Name:	argA HAMAP MF_01105
Ordered Locus Names:	Daci_4573

Organism

Delftia acidovorans (strain DSM 14801 / SPH-1) [Complete proteome] [HAMAP]

Taxonomic identifier

398578 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Delftia

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01105 SAAS SAAS010167
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01105 SAAS SAAS010167
Subcellular location	Cytoplasm By similarity HAMAP MF_01105 SAAS SAAS010167.
Miscellaneous	In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role By similarity. HAMAP MF_01105
Sequence similarities	Belongs to the acetyltransferase family. ArgA subfamily. HAMAP MF_01105 Contains 1 N-acetyltransferase domain. HAMAP MF_01105 SAAS SAAS010167

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_01105 SAAS SAAS010167
Cellular component	Cytoplasm HAMAP MF_01105 SAAS SAAS010167
Molecular function	Acyltransferase HAMAP MF_01105 SAAS SAAS010167 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acetyl-CoA:L-glutamate N-acetyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	302 – 438	137	N-acetyltransferase By similarity HAMAP MF_01105

Sequences

	Sequence		Length	Mass (Da)
	A9C391 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 4377AA0C1FDCF615	FASTA	448	49,499
	10 20 30 40 50 60 MSTVFNFTFV PWFRSVAPYI HKFRHQTFVV GLTGEAIASG KLSSIVQDLA MIQAMGVKIV 70 80 90 100 110 120 LVHGFRPQVN EQLAAKGHEA QYSRGVRITD SVALDCAQEA AGQLRYEIEA AFSQGLPNTP 130 140 150 160 170 180 MAGARVRVIS GNFLTARPVG IVDGVDFKHS GLVRKVDVSG IRSALDMDAM VLMSPFGFSP 190 200 210 220 230 240 TGEAFNLSME EVATRVAIEL KADKLIFMTE VPGIRMDPTG PADETNPIDT ELPLATARRM 250 260 270 280 290 300 LAELPTPEQP TDTGFYLQHC VHACEHGVER SHILPFAIDG ALLLEIYVHD GIGTMIIDEK 310 320 330 340 350 360 LEELREATPD DVAGIIQLIE PFEKDGTLVK RSRTEIERDI AHYTIIEHDG VIFGCAALYP 370 380 390 400 410 420 YPSARTAEMA AVTVSPKSQG TGDGEKLLKR IEQRAKAQGL DSLFVLTTRT MHWFIKRGFQ 430 440 PVDPDWLPEA RKAKYNWDRK SQVLVKKL

References

[1]

"Complete sequence of Delftia acidovorans DSM 14801 / SPH-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Schleheck D., Richardson P. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000884 Genomic DNA. Translation: ABX37202.1.
RefSeq	YP_001565587.1. NC_010002.1.
3D structure databases
ProteinModelPortal	A9C391.
ModBase	Search...
Protein-protein interaction databases
STRING	A9C391.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5750161.
GenomeReviews	Gene locus Daci_4573 in contig CP000884_GR.
KEGG	dac:Daci_4573.
PATRIC	21643089. VBIDelAci41351_4597.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG545264.
OMA	AFNLAME.
ProtClustDB	PRK05279.
Family and domain databases
HAMAP	MF_01105. N_acetyl_glu_synth. [Tree]
InterPro	IPR000182. AcTrfase_GCN5-related_dom. IPR016181. Acyl_CoA_acyltransferase. IPR001048. Asp/Glu/Uridylate_kinase. IPR010167. NH2A_AcTrfase_ArgA. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit. G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
KO	K14682.
Pfam	PF00696. AA_kinase. 1 hit. PF00583. Acetyltransf_1. 1 hit. [Graphical view]
PIRSF	PIRSF000423. ArgA. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit. SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITE	PS51186. GNAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9C391_DELAS

Accession

Primary (citable) accession number: A9C391

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)