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A9C020

- GCH4_DELAS

UniProt

A9C020 - GCH4_DELAS

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Protein
GTP cyclohydrolase FolE2
Gene
folE2, Daci_3650
Organism
Delftia acidovorans (strain DSM 14801 / SPH-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate By similarity.UniRule annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei156 – 1561May be catalytically important By similarity

GO - Molecular functioni

  1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciDACI398578:GHK3-3697-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2 (EC:3.5.4.16)
Gene namesi
Name:folE2
Ordered Locus Names:Daci_3650
OrganismiDelftia acidovorans (strain DSM 14801 / SPH-1)
Taxonomic identifieri398578 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeDelftia
ProteomesiUP000000784: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296GTP cyclohydrolase FolE2UniRule annotation
PRO_0000372026Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi398578.Daci_3650.

Structurei

3D structure databases

ProteinModelPortaliA9C020.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1469.
HOGENOMiHOG000247517.
KOiK09007.
OMAiAGRTTIQ.
OrthoDBiEOG6X6RBH.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B.
InterProiIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view]
PfamiPF02649. GCHY-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9C020-1 [UniParc]FASTAAdd to Basket

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MLAPLPDVSL TDPAPSLSPL QWVGMQGIDL PVTVAEPGYW RELHARADVQ    50
VDLPAAHVKG IHMSRLYRQL DSLAEESALS ALALRHALQA MIDSHLDCQS 100
RSARMRLSLD LLAQRPALVT HDLSGWKSYP VRLDATLAQG VFQLRLQVGV 150
GYSSTCPCSA ALSRQLLEQG FLQAFAGEPL VEPDQVASWL RRHGTLATAH 200
SQRSEAQVSV DLACDAPDLG ILPLIARVEQ ALGTPVQTAV KRADEQAFAA 250
LNGRNLMFVE DAARRIQAAL EGIYARPRVH VRHMESLHPH DAVAWA 296
Length:296
Mass (Da):32,306
Last modified:January 15, 2008 - v1
Checksum:i978F17C3BFB5352F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000884 Genomic DNA. Translation: ABX36282.1.
RefSeqiYP_001564667.1. NC_010002.1.

Genome annotation databases

EnsemblBacteriaiABX36282; ABX36282; Daci_3650.
GeneIDi5749233.
KEGGidac:Daci_3650.
PATRICi21641253. VBIDelAci41351_3684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000884 Genomic DNA. Translation: ABX36282.1 .
RefSeqi YP_001564667.1. NC_010002.1.

3D structure databases

ProteinModelPortali A9C020.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 398578.Daci_3650.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX36282 ; ABX36282 ; Daci_3650 .
GeneIDi 5749233.
KEGGi dac:Daci_3650.
PATRICi 21641253. VBIDelAci41351_3684.

Phylogenomic databases

eggNOGi COG1469.
HOGENOMi HOG000247517.
KOi K09007.
OMAi AGRTTIQ.
OrthoDBi EOG6X6RBH.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci DACI398578:GHK3-3697-MONOMER.

Family and domain databases

HAMAPi MF_01527_B. GTP_cyclohydrol_B.
InterProi IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view ]
Pfami PF02649. GCHY-1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Delftia acidovorans DSM 14801 / SPH-1."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Schleheck D., Richardson P.
    Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14801 / SPH-1.

Entry informationi

Entry nameiGCH4_DELAS
AccessioniPrimary (citable) accession number: A9C020
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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