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A9BWD8 (A9BWD8_DELAS) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138
Ordered Locus Names:Daci_3522 EMBL ABX36158.1
OrganismDelftia acidovorans (strain DSM 14801 / SPH-1) [Complete proteome] [HAMAP] EMBL ABX36158.1
Taxonomic identifier398578 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Delftia ›

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain108 – 319212ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding134 – 19966ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2891Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2911Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
A9BWD8 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 72AD8B92948C37CA

FASTA42745,251
        10         20         30         40         50         60 
MKILVIGGGG REHALAWKLA ESPKSTKVYV APGNGGTGLA GGKVENLNIT DPQALREWAQ 

        70         80         90        100        110        120 
AEKVALTVVG PEAPLAAGVV DEFRAHGLRI FGPSKAAAQL ESSKAFSKDF MARHGIPTAL 

       130        140        150        160        170        180 
YETFTDPVAA HAYVDRLGAP IVVKADGLAA GKGVVVATTL QEAHDAVDFM LVDNKYGVAH 

       190        200        210        220        230        240 
NDGGARVVIE EFLAGEEASF IVLCDGKNVL ALATSQDHKR LKDGDQGPNT GGMGAYSPAP 

       250        260        270        280        290        300 
VVTADVHARA MREIILPTIR GMEKDGIPYT GFLYAGLMID ASGHPKTLEF NCRMGDPETQ 

       310        320        330        340        350        360 
PIMMRLKSDL VDVMLAATDA KLDQVELQWD RRTALGVVMA AAGYPEDPRK GDAISGLPQD 

       370        380        390        400        410        420 
AADAMVFHAG TQLKDGVPVT SGGRVLCVTV LADSVKQAQQ KVYDVARGIH FDGAQYRRDI 


GFRAVKN

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References

[1]"Complete sequence of Delftia acidovorans DSM 14801 / SPH-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Schleheck D., Richardson P.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14801 / SPH-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000884 Genomic DNA. Translation: ABX36158.1.
RefSeqYP_001564543.1. NC_010002.1.

3D structure databases

ProteinModelPortalA9BWD8.
SMRA9BWD8. Positions 1-426.
ModBaseSearch...

Protein-protein interaction databases

STRING398578.Daci_3522.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX36158; ABX36158; Daci_3522.
GeneID5749107.
KEGGdac:Daci_3522.
PATRIC21641001. VBIDelAci41351_3558.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0151.
HOGENOMHOG000033463.
KOK01945.
OMAMGAYTPL.
ProtClustDBPRK00885.

Enzyme and pathway databases

BioCycDACI398578:GHK3-3571-MONOMER.
UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9BWD8_DELAS
AccessionPrimary (citable) accession number: A9BWD8
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 29, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info