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A9BS60 (PYRF_DELAS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:Daci_0824
OrganismDelftia acidovorans (strain DSM 14801 / SPH-1) [Complete proteome] [HAMAP]
Taxonomic identifier398578 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeDelftia

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 275275Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000138950

Sites

Active site951Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A9BS60 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 720FA57F85DA209F

FASTA27529,285
        10         20         30         40         50         60 
MTFLDMLRNA TAQNQSMLCV GLDPEPSRFP AAMRGDASKI YDFCAAIVDA TADLVNSFKP 

        70         80         90        100        110        120 
QIAYFAAHRA EDQLEKLMAH MRAVAPHVPI ILDAKRGDIG STAEQYAKEA FERYGADAVT 

       130        140        150        160        170        180 
LSPFMGFDSI TPYLQYEGKG AFLLCRTSNP GGDDLQAQRL ADLPGQPHLF EHVARLAQGP 

       190        200        210        220        230        240 
WNTNGQLGLV VGATRPQEIE RVREFAPSLP LLIPGVGAQG GDAVATVKAA RIGGGPIIIN 

       250        260        270 
SSRAVLYASQ GDDFAAAART AAQATRQTLQ DAAAA 

« Hide

References

[1]"Complete sequence of Delftia acidovorans DSM 14801 / SPH-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Schleheck D., Richardson P.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14801 / SPH-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000884 Genomic DNA. Translation: ABX33470.1.
RefSeqYP_001561855.1. NC_010002.1.

3D structure databases

ProteinModelPortalA9BS60.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING398578.Daci_0824.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX33470; ABX33470; Daci_0824.
GeneID5746378.
KEGGdac:Daci_0824.
PATRIC21635515. VBIDelAci41351_0845.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMACRTSNAG.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycDACI398578:GHK3-842-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_DELAS
AccessionPrimary (citable) accession number: A9BS60
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways