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A9BRF4 (SYR_DELAS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Daci_0669
OrganismDelftia acidovorans (strain DSM 14801 / SPH-1) [Complete proteome] [HAMAP]
Taxonomic identifier398578 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeDelftia

Protein attributes

Sequence length565 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 565565Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095358

Regions

Motif128 – 13811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A9BRF4 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 43BD7C1DEFC030BC

FASTA56562,537
        10         20         30         40         50         60 
MLSVKQELLA ALAGELETLS PGAGARAAFE SPKVAAHGDF ACTAAMQLAK PLKLNPRSLG 

        70         80         90        100        110        120 
EQLKAALEAT PSFQRWVDAI EIAGPGFLNI RLKPAAKQQI IREVLEQAEK FGWLADRGAK 

       130        140        150        160        170        180 
MLVEFVSANP TGPLHVGHGR QAALGDAICN LYATQGWGVH REFYYNDAGV QIDTLTKSTQ 

       190        200        210        220        230        240 
LRAKGFKPGD ECWPIDPENP ASKAFYNGSY IQDIADDFLA CKTVKADDRE FTANGDVEDY 

       250        260        270        280        290        300 
DNIRQFAVAY LRNEQDKDLQ AFNLHFDEYY LESSLYTNGY VEDAVQRLIA GGHTYELDGA 

       310        320        330        340        350        360 
LWLKSTDYGD DKDRVMRKQD GNYTYFVPDV AYHIQKFKRG YSKVVNIQGT DHHGTIARVR 

       370        380        390        400        410        420 
AGLQAADVGI PAGYPDYVLH TMVRVVRGGE EVKISKRAGS YVTLRDLIEW TSKDAVRFFL 

       430        440        450        460        470        480 
LSRKPDTEYT FDVDLAVAQN NDNPVYYVQY AHARICSVLA AWGGDAATLK DVDLSALEGP 

       490        500        510        520        530        540 
QAQALMLQLA KYPAMLTSAA EGNAPHDVTF YLRELASLYH SYYDAERILV DDEKVKLARL 

       550        560 
ALISATRQVL HNGLAVLGVS APQRM 

« Hide

References

[1]"Complete sequence of Delftia acidovorans DSM 14801 / SPH-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Schleheck D., Richardson P.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14801 / SPH-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000884 Genomic DNA. Translation: ABX33315.1.
RefSeqYP_001561700.1. NC_010002.1.

3D structure databases

ProteinModelPortalA9BRF4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING398578.Daci_0669.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX33315; ABX33315; Daci_0669.
GeneID5746222.
KEGGdac:Daci_0669.
PATRIC21635193. VBIDelAci41351_0685.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycDACI398578:GHK3-686-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_DELAS
AccessionPrimary (citable) accession number: A9BRF4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries