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A9BJH6

- PYRF_PETMO

UniProt

A9BJH6 - PYRF_PETMO

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Protein
Orotidine 5'-phosphate decarboxylase
Gene
pyrF, Pmob_0659
Organism
Petrotoga mobilis (strain DSM 10674 / SJ95)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei97 – 971Proton donor By similarity

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciPMOB403833:GH51-682-MONOMER.
UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
Alternative name(s):
OMP decarboxylase
Short name:
OMPDCase
Short name:
OMPdecase
Gene namesi
Name:pyrF
Ordered Locus Names:Pmob_0659
OrganismiPetrotoga mobilis (strain DSM 10674 / SJ95)
Taxonomic identifieri403833 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaePetrotoga
ProteomesiUP000000789: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289Orotidine 5'-phosphate decarboxylaseUniRule annotation
PRO_1000085575Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi403833.Pmob_0659.

Structurei

3D structure databases

ProteinModelPortaliA9BJH6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000245747.
KOiK01591.
OMAiCRTSNAG.
OrthoDBiEOG6DZF33.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01215. OMPdecase_type2.
InterProiIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.

Sequencei

Sequence statusi: Complete.

A9BJH6-1 [UniParc]FASTAAdd to Basket

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MIIDRLFNEV EKKGNVCVGL DTHLDYIPVN LKEKYQDIDE ILFEFNKEII    50
DKTYDLVPVY KLQIAYYEAY GIKGLLGYKK TIEYLRSIKK ITIGDIKRGD 100
ISSTAQMYAK AHFEGEFEVD FVTLNPYLGF DSLTPYLKYI ESGEKGVFVL 150
LRTSNPGAKD IQYLKVSPKD EYLYYIVGDK LNEIGVKYRG SCGYSSIGAV 200
VGGTHIEEAK EIRNRYKNMF FLIPGYGHQG ATGKDVSLYL NKGNGGVINS 250
SRGIITAYKN YKDGDQRFAD YARKAVLDMR EDIQSERGV 289
Length:289
Mass (Da):32,855
Last modified:January 15, 2008 - v1
Checksum:i8654A335AC7D9AB3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000879 Genomic DNA. Translation: ABX31390.1.
RefSeqiYP_001567713.1. NC_010003.1.

Genome annotation databases

EnsemblBacteriaiABX31390; ABX31390; Pmob_0659.
GeneIDi5756895.
KEGGipmo:Pmob_0659.
PATRICi22918906. VBIPetMob40494_0686.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000879 Genomic DNA. Translation: ABX31390.1 .
RefSeqi YP_001567713.1. NC_010003.1.

3D structure databases

ProteinModelPortali A9BJH6.
ModBasei Search...

Protein-protein interaction databases

STRINGi 403833.Pmob_0659.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX31390 ; ABX31390 ; Pmob_0659 .
GeneIDi 5756895.
KEGGi pmo:Pmob_0659.
PATRICi 22918906. VBIPetMob40494_0686.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000245747.
KOi K01591.
OMAi CRTSNAG.
OrthoDBi EOG6DZF33.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .
BioCyci PMOB403833:GH51-682-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01215. OMPdecase_type2.
InterProi IPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10674 / SJ95.

Entry informationi

Entry nameiPYRF_PETMO
AccessioniPrimary (citable) accession number: A9BJH6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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