SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A9BF22

- SYL_PETMO

UniProt

A9BF22 - SYL_PETMO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Leucine--tRNA ligase
Gene
leuS, Pmob_0344
Organism
Petrotoga mobilis (strain DSM 10674 / SJ95)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei585 – 5851ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMOB403833:GH51-352-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:Pmob_0344
OrganismiPetrotoga mobilis (strain DSM 10674 / SJ95)
Taxonomic identifieri403833 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaePetrotoga
ProteomesiUP000000789: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 828828Leucine--tRNA ligaseUniRule annotation
PRO_1000199217Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi403833.Pmob_0344.

Structurei

3D structure databases

ProteinModelPortaliA9BF22.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 5211"HIGH" regionUniRule annotation
Add
BLAST
Motifi582 – 5865"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9BF22-1 [UniParc]FASTAAdd to Basket

« Hide

MEKTYNPQEI ERKWQRNWQE KDAFKVSNEE YHKKYYDLVM FPYPSGTLHV    50
GHVKNYVIGD VIARYKRMRG YNVMHPFGFD AFGLPAENAA IEKGNIHPED 100
WTMQNINIIR NQIKKLGISY NWEREVITCK EDYYKWTQWI FLQLYKNGLA 150
YKKKAPVNWC PNCKTVLANE QVVNGKCERC GTVVEIKQLE QWYFKITDYA 200
EKLLYDLEKL SGWPENVKIM QKNWIGKSVG AEVEFNLDNG KGSLRVFTTR 250
PDTLWGVTFM ALAPESPLVE ELTTPENSEK VNQFLQRVSL QDRFKRTAEG 300
AEKEGVFTGS YAINPVNGEK IPIYVANYIL YEYGTGAIMA VPAHDQRDFE 350
FAKKYDLPIR IVIMPEGDEL TEENLEKAYI GEGVLVNSGE FTGLDNQTAI 400
REVSQWLEDK KIGKVVTQYK LRDWLISRQR YWGAPIPVVY CEKCGVVPVP 450
EKDLPVKLPR DVAFEPTGKS PLIDHPDFKE TTCPKCGGKA KREVDTMDTF 500
VDSSWYYLRY VNPKLEDKPF NKEDVDNWLP VDQYIGGVEH AILHLLYSRF 550
ITKVLKDLGY VSFDEPFKNL FTQGMIYRNG AKMSKSKGNV VSPEEMIEKY 600
GTDALRTYIL FMAPPERDAE WNDSGIEGTY RFLNKVWNTY MKIQDKIIHL 650
ENKPNYPLKN KSEKDLRRKL HQTIEKITSD IEGNFQFNTA VSSLMELLNE 700
LNSYLNNTDD KDWNLNLLKE FSEDFVLMLS PIAPHISEEL WKNFGKDEFI 750
FKASWPEIDK NALKAEEITL AVQINGKLRA QITVDVSLNE DEVKSYALED 800
DKVQKYISGK KIQKIIYVPK KIINIVVK 828
Length:828
Mass (Da):96,100
Last modified:January 15, 2008 - v1
Checksum:iF65300E294F9C3E0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000879 Genomic DNA. Translation: ABX31086.1.
RefSeqiYP_001567409.1. NC_010003.1.

Genome annotation databases

EnsemblBacteriaiABX31086; ABX31086; Pmob_0344.
GeneIDi5758364.
KEGGipmo:Pmob_0344.
PATRICi22918226. VBIPetMob40494_0360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000879 Genomic DNA. Translation: ABX31086.1 .
RefSeqi YP_001567409.1. NC_010003.1.

3D structure databases

ProteinModelPortali A9BF22.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 403833.Pmob_0344.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX31086 ; ABX31086 ; Pmob_0344 .
GeneIDi 5758364.
KEGGi pmo:Pmob_0344.
PATRICi 22918226. VBIPetMob40494_0360.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci PMOB403833:GH51-352-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10674 / SJ95.

Entry informationi

Entry nameiSYL_PETMO
AccessioniPrimary (citable) accession number: A9BF22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi