A9BE38 (MQO_PROM4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	P9211_04171

Organism

Prochlorococcus marinus (strain MIT 9211) [Complete proteome] [HAMAP]

Taxonomic identifier

93059 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000099878

Sequences

	Sequence		Length	Mass (Da)
	A9BE38 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: A24CB79B1F26BEAE	FASTA	500	55,497
	10 20 30 40 50 60 MFISEAIGPE DRFDAVLIGA GIMSSTLAVL LHELDPCMRI LIVERLDSPA LESTSAFNNS 70 80 90 100 110 120 GTGHAANCEF NYTPLQSNGR IEIEKALSIN SSFERSLEFW ASLAEMGRIS PATFLNFLPH 130 140 150 160 170 180 ISFVWKEADL DFLKQRYLQL SSEVAFQRME WSDDKAELKE WMPIVMQGRP TSEKVAATRI 190 200 210 220 230 240 QRGTDVDFGA LTRAYFDSLE ESGSVHIRLS TEVIDIQRFG QDPWKLFLKS DLNSYCVEGK 250 260 270 280 290 300 FVFLGAGGGA LSLLQKSGIP EGKFYGGFPV SGQWLVCNET QVTNNHNAKV YGNADVGSPP 310 320 330 340 350 360 MSVPHLDTRW IRGRKSLLFG PFAGFNTKFL KYGSNWDLFR SIQMGNVGAM VQAGLENIDL 370 380 390 400 410 420 IKYLYGQLQQ DHISRVDSLQ NFLPNAKSKD WHLSLAGQRV QIIKKTSKGG KLKMGTEMVS 430 440 450 460 470 480 SSDGSLAALL GASPGASTAV AIMIDLLRSS WGEKMSTKIW QDRLRRLIPS FGEDLNSNES 490 500 MLKATRDRND SLLGFGEKNQ

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9211.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000878 Genomic DNA. Translation: ABX08348.1.
RefSeq	YP_001550302.1. NC_009976.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A9BE38.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5731256.
GenomeReviews	Gene locus P9211_04171 in contig CP000878_GR.
KEGG	pmj:P9211_04171.
PATRIC	22986316. VBIProMar136502_0443.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	NTQFEVS.
PhylomeDB	A9BE38.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_PROM4

Accession

Primary (citable) accession number: A9BE38

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program