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A9BDF0 (SYR_PROM4) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:P9211_02051
OrganismProchlorococcus marinus (strain MIT 9211) [Complete proteome] [HAMAP]
Taxonomic identifier93059 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length603 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 603603Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095392

Regions

Motif143 – 15311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A9BDF0 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 46FDFF979FF8E28F

FASTA60367,784
        10         20         30         40         50         60 
MRNIYLALNQ HICGALEAAF PQASLVAKQS GQSLNPQLVP ATKPEFGDFQ VNGALALSKI 

        70         80         90        100        110        120 
LKKAPRKIAE EIIKQLVKND DFNKLCLKPE IAGPGFINLT IQNSCLTTEI CARLNDDHLG 

       130        140        150        160        170        180 
VPIAKPLKTH KSLKPIVVDF SSPNIAKEMH VGHLRSTIIG DSIARVLEFR GHPVLRLNHV 

       190        200        210        220        230        240 
GDWGTQFGML ITYLKLVAPE ALTTANAINL GDLVKFYRQA KKLFDEDETF QDASREEVVR 

       250        260        270        280        290        300 
LQNGDPQSLK AWQLLCDQSR IEFEKIYKRL DIHITERGES FYNQYLQDVI DDLKSTNLLV 

       310        320        330        340        350        360 
TDNGAKCIFL DDITGKDGKP LPLIVQKTDG GFNYATTDLA AIRYRLQAYP QGDGACRLIY 

       370        380        390        400        410        420 
VTDAGQASHF FAVFQVARRA NWIPNDCRIE HVPFGLVQGE DGKKLKTRSG DTVRLKDLLD 

       430        440        450        460        470        480 
EAIIRAKNDL EERLNAEGRK EDQEFINKVS RVIGIAAVKY ADLSQNRITN YQFSFNRMLA 

       490        500        510        520        530        540 
LQGNTAPYLL YALVRIAGIN RKGGSLNATI NKLTFNEPQE WMLARELLKF DEVILQVEEE 

       550        560        570        580        590        600 
LLPNRLCNYL FELSQVFNRF YDQVPVLKAN DSLKASRLAL CQLTADTIKL GLKLLGIPTL 


DRM 

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9211.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000878 Genomic DNA. Translation: ABX08136.1.
RefSeqYP_001550090.1. NC_009976.1.

3D structure databases

ProteinModelPortalA9BDF0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING93059.P9211_02051.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX08136; ABX08136; P9211_02051.
GeneID5730060.
KEGGpmj:P9211_02051.
PATRIC22985836. VBIProMar136502_0215.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycPMAR93059:GHJV-208-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PROM4
AccessionPrimary (citable) accession number: A9BDF0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: April 16, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries