A9BBV6 (A9BBV6_PROM4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401

Gene names

Name:	msrA2 HAMAP MF_01401
Ordered Locus Names:	P9211_13871

Organism

Prochlorococcus marinus (strain MIT 9211) [Complete proteome] [HAMAP] EMBL ABX09318.1

Taxonomic identifier

93059 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABX09318.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	40	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A9BBV6 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 990236CE963754EF	FASTA	211	24,220
	10 20 30 40 50 60 MKLPLFKKII PLLAIAFSLL FSSPYAAVAS LEKAVLAGGC FWCLEHDLEE LPGILSVESG 70 80 90 100 110 120 YTGGNLQNPT YKNHKGHQEA VIVEFDTKKI AFDKLLRSYW RNIDPFDSRG QFCDRGDSYR 130 140 150 160 170 180 PVIFARDDSQ LKESIESLSF ASKELSASID DIKVEIKNAN KFWQAEDYHQ NFAENNNLKY 190 200 210 QFYRYSCGRD KRLNEVWGST SRKDLPWSIN N

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000878 Genomic DNA. Translation: ABX09318.1.
RefSeq	YP_001551272.1. NC_009976.1.
3D structure databases
ProteinModelPortal	A9BBV6.
ModBase	Search...
Protein-protein interaction databases
STRING	A9BBV6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5731595.
GenomeReviews	Gene locus P9211_13871 in contig CP000878_GR.
KEGG	pmj:P9211_13871.
PATRIC	22988398. VBIProMar136502_1467.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG748152.
OMA	HKGHQEA.
PhylomeDB	A9BBV6.
ProtClustDB	CLSK919692.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9BBV6_PROM4

Accession

Primary (citable) accession number: A9BBV6

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)