A9BBN4 (SURE_PROM4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	P9211_13151

Organism

Prochlorococcus marinus (strain MIT 9211) [Complete proteome] [HAMAP]

Taxonomic identifier

93059 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	5'-nucleotidase surE HAMAP MF_00060		PRO_1000092025
Sites
	Metal binding	11	1	Divalent metal cation By similarity
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	43	1	Divalent metal cation By similarity
	Metal binding	101	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9BBN4 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: C9662155367AAB44	FASTA	269	29,159
	10 20 30 40 50 60 MKPLKILISN DDGVFAEGIR TLAGAAAFRG HQVTVVCPDQ ERSATGHGLT LHSPIRAEKA 70 80 90 100 110 120 NELFGKGVSA WGCNGTPADC VKLALNEILP EKPDLILSGI NHGPNLGTDI FCSGTVAAAL 130 140 150 160 170 180 EGTLAGIPAI AISIASFQWR DFSFASQLAL EIAEEALTKN WPQKLLLNIN TPPCKSSEMG 190 200 210 220 230 240 QLGWTRLSIR QYEEQFTRRI DPRGNPYYWM AGNAVKDIDS AGDGPSQWPS DVAQIESNSP 250 260 SITPIEPDLF WRGNISDLPA INLKNYFSR

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9211.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000878 Genomic DNA. Translation: ABX09246.1.
RefSeq	YP_001551200.1. NC_009976.1.
3D structure databases
ProteinModelPortal	A9BBN4.
ModBase	Search...
Protein-protein interaction databases
STRING	A9BBN4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5731546.
GenomeReviews	Gene locus P9211_13151 in contig CP000878_GR.
KEGG	pmj:P9211_13151.
PATRIC	22988234. VBIProMar136502_1389.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	NGFYYVN.
PhylomeDB	A9BBN4.
ProtClustDB	PRK00346.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_PROM4

Accession

Primary (citable) accession number: A9BBN4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program