A9BBH9 (SYGA_PROM4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	P9211_12601

Organism

Prochlorococcus marinus (strain MIT 9211) [Complete proteome] [HAMAP]

Taxonomic identifier

93059 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000101215

Sequences

	Sequence		Length	Mass (Da)
	A9BBH9 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: CF4EDC3277A9D658	FASTA	293	33,714
	10 20 30 40 50 60 MHFQDIISSL NSFWSKQGCL LLQPYDTEKG AGTMSPHTFL RAIGPEPWAV AYPEPCRRPT 70 80 90 100 110 120 DGRYGDNPNR AQHYFQYQVL IKPSFDGIQE TYLSSLEIIG IDPKDHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGVGWEVW LDGMEVTQFT YFQQCGGLDC KPVSIEITYG LERLAMYLQN VDCIWDLSWN 190 200 210 220 230 240 QTYKYGDIWL DLEKSNCKYN FEFSNPKRLK ELFEIYEGEA SDLVLNKLPG PALDFVLKCS 250 260 270 280 290 HTFNLLEARG VISVTERTST IGRIRNLARK VAELWLEERQ ALGFPLLEGD AKE

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9211.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000878 Genomic DNA. Translation: ABX09191.1.
RefSeq	YP_001551145.1. NC_009976.1.
3D structure databases
ProteinModelPortal	A9BBH9.
SMR	A9BBH9. Positions 1-277.
ModBase	Search...
Protein-protein interaction databases
STRING	A9BBH9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5731385.
GenomeReviews	Gene locus P9211_12601 in contig CP000878_GR.
KEGG	pmj:P9211_12601.
PATRIC	22988122. VBIProMar136502_1335.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	A9BBH9.
ProtClustDB	PRK09348.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_PROM4

Accession

Primary (citable) accession number: A9BBH9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program