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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Prochlorococcus marinus (strain MIT 9211)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei359 – 3591UniRule annotation
Active sitei460 – 4601UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPMAR93059:GHJV-899-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:P9211_08741
OrganismiProchlorococcus marinus (strain MIT 9211)
Taxonomic identifieri93059 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000000788 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 532532Glucose-6-phosphate isomerasePRO_1000125743Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi93059.P9211_08741.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9BAE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLPDYSPNN SSLQWERFSE LLWHNEELGL WVDISRMNVN EHELKELKPI
60 70 80 90 100
FQKAFEAMNS LEKGSMANID EERMVGHYWL RNPDLAPSRD ISKLIANQIS
110 120 130 140 150
QIEQFTTSIL SGDIRSDAGE LFTDVLWIGI GGSGLGPLLL IESLQELNKG
160 170 180 190 200
LKFHFLDNVD PIGIDKKLEL LQSKLSTTLF VVVSKSGGTP EPQIAMDQAR
210 220 230 240 250
HVVETNGKNW PTRSVAITMC NSLLDNKAKQ ENWLKTFDLP DWVGGRTSIT
260 270 280 290 300
GAVGLLPLGL IDSDLKSFLL GASKMDELTR NNELLDNPAA LMAMAWYSSG
310 320 330 340 350
SAKGLKDMVV LPYRDSLEVF SRYLQQLVME SLGKKNDREG NIVFQGLSVY
360 370 380 390 400
GNKGSTDQHA YVQQLRDGIN NFFVTFIEVL TNNESPCLNN KLPGDYLSGF
410 420 430 440 450
MQGTRLALSD SNRQSLTITL KTFDPLSLGA LIALFERTVG LYAELININA
460 470 480 490 500
YHQPGVEAGK KAAADILNLQ LQIEDILSDY SNYSIEQIST RLSSSNSESI
510 520 530
YFILRNLVFN NKYSAKGSWK NPSSLIFKRE KL
Length:532
Mass (Da):59,492
Last modified:January 14, 2008 - v1
Checksum:i5DBA6FBEADF5E3BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000878 Genomic DNA. Translation: ABX08805.1.
RefSeqiYP_001550759.1. NC_009976.1.

Genome annotation databases

EnsemblBacteriaiABX08805; ABX08805; P9211_08741.
KEGGipmj:P9211_08741.
PATRICi22987308. VBIProMar136502_0932.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000878 Genomic DNA. Translation: ABX08805.1.
RefSeqiYP_001550759.1. NC_009976.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93059.P9211_08741.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX08805; ABX08805; P9211_08741.
KEGGipmj:P9211_08741.
PATRICi22987308. VBIProMar136502_0932.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciPMAR93059:GHJV-899-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9211.

Entry informationi

Entry nameiG6PI_PROM4
AccessioniPrimary (citable) accession number: A9BAE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2009
Last sequence update: January 14, 2008
Last modified: March 31, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.