A9B5H8LEXA_HERA2LexA repressor3.4.21.88lexAHaur_0151Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)BacteriaChloroflexotaChloroflexiaHerpetosiphonalesHerpetosiphonaceaeHerpetosiphonComplete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.Hydrolysis of Ala-|-Gly bond in repressor LexA.Homodimer.Belongs to the peptidase S24 family.Autocatalytic cleavageDNA damageDNA repairDNA replicationDNA-bindingHydrolaseRepressorSOS responseTranscriptionTranscription regulationMSGLSQRQQRIYDYIKQFIRTNGYAPAIRDIQRELSISSTSVVAYNLRALESKGHIRREGNISRAIELINAEQPLPTVLGGQRVPVLGVIAAGQPIPVPNDSANSDDSVLVPEEIVGNDKLGDVYALRVKGYSMVDALIADGDIVLLRYQATAENGEMVAARIRDENEVTLKRIYWEGDRVRLQPANVTMEAMYYPSTNVEVQGRVVGVIRNLG
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